Chapter 8: Mitosis - Cell Division and Reproduction
Chapter 8: Mitosis - Cell Division and Reproduction
Chapter 8: Mitosis - Cell Division and Reproduction
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External Factors Control <strong>Mitosis</strong><br />
1. Anchorage<br />
Most cells cannot divide unless they are attached<br />
to a solid surface.<br />
May prevent inappropriate growth of detached cells<br />
2. Nutrients <strong>and</strong> growth factors<br />
Lack of nutrients can limit mitosis<br />
Growth factors: Proteins that stimulate cell<br />
division.<br />
3. <strong>Cell</strong> density<br />
Density-dependent inhibition: Cultured cells will<br />
stop dividing after a single layer covers the petri<br />
dish. <strong>Mitosis</strong> is inhibited by high cell density.<br />
Cancer cells do not demonstrate density inhibition
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