Chapter 8: Mitosis - Cell Division and Reproduction

Mitosis: The Stages of Cell Division
1. Prophase
Chromatin condenses into chromosomes, which appear
as two sister chromatids joined by a centromere.
Nucleoli disappear.
Nuclear envelope breaks apart.
In animal cells, mitotic spindle begins to form as
mictotubules grow out of two centrosomes or
microtubule organizing centers (MTOCs).
• Each centrosome is made up of a pair of centrioles.
Microtubules attach to kinetochores on chromatids and
begin to move chromosomes towards center of cell.
Centrosomes begin migrating to opposite poles of cell.