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Safety issues with transdermal opioid medications - Australian and ...

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Did the Alert make a difference?<br />

• “Despite these efforts FDA has continued<br />

to receive reports of death <strong>and</strong> life-<br />

threatening adverse events .. when the<br />

fentanyl patch was:<br />

• used to treat pain in <strong>opioid</strong>-na<br />

naïve patients<br />

• <strong>opioid</strong>-tolerant patients have applied more<br />

patches than prescribed,<br />

• changed the patch too frequently,<br />

• <strong>and</strong> exposed the patch to a heat source. “

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