efsa-opinion-chromium-food-drinking-water
efsa-opinion-chromium-food-drinking-water efsa-opinion-chromium-food-drinking-water
Chromium in food and drinking water concentration of 2 g/L in human milk was selected. This selection was based on the upper value of the range of mean total Cr concentrations described among most of the European studies on breast milk samples, 0.14-1.80 µg/L (see Section 4.1.3 and Appendix D). The mean dietary exposure for an infant of 6.1 kg exclusively fed with human milk was estimated to be 0.3 g/kg b.w. per day, while for the same infant with high consumption the dietary exposure would be 0.4 g/kg b.w. per day. Nine dietary surveys were available for ‘Toddlers’. This age class showed the highest exposure to Cr(III). The mean dietary exposure to Cr(III) ranged from 2.3 μg/kg b.w. per day to 5.9 μg/kg b.w. per day (minimum LB and maximum UB across European dietary surveys, respectively). The 95 th percentile dietary exposure estimates ranged from a minimum LB of 3.4 μg/kg b.w. per day to a maximum UB of 9.0 μg/kg b.w. per day. In the toddler population the exposure to Cr(III) was in general mainly due to ‘Foods for infants and small children’ (1-26 % of the total, median = 9 %), ‘Milk and dairy products’ (9-25 % of the total, median = 14 %), and ‘Bread and rolls’ (0.3-12 % of the total, median = 10 %) (Figure 10). In some dietary surveys ‘Chocolate (cocoa) products’ also made an important contribution to the dietary exposure to Cr(III). The contribution of the food group ‘Vegetables and vegetable products (including fungi)’ ranged between 3 % and 8 % of the total (median = 6 %). In one survey the reported consumption of cocoa powder led to the food group ‘Non-alcoholic beverages’ to contribute up to 45 % of the total exposure to Cr(III). However, the consumption data from this dietary survey refers only to 17 individuals and, therefore, this value could not be representative. INRAN_SCAI_2005_06 NUTRICHILD Milk and dairy products Food for infants and small children Bread and rolls enKid VCP_kids INRAN_SCAI_2005_06 DONALD 2008 DONALD 2007 DONALD 2006 DIPP NUTRICHILD Regional_Flanders 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% % Chocolate (Cocoa) products Vegetables and vegetable products (including fungi) Fruit and fruit products Meat and meat products (including edible offal) Potatoes and potatoes products Sugar and confectionary (non chocolate products) Composite food (including frozen products) Animal and vegetable fats and oils Biscuits (cookies) Fish and other seafood (including amphibians, reptiles, snails and insects) Non-alcoholic beverages (excepting milk based beverages) Rest of food categories Figure 10: Main food groups contributing (%) to the chronic dietary exposure to Cr(III) for the age classes ‘Infants’ (from the top the two first surveys) and ‘Toddlers’. Data are presented by individual dietary surveys across Europe using LB estimations. The names on the left refer to the names of the different surveys (see Appendix F for more details). 6.1.2.2. Other children A total of 17 dietary surveys were available to evaluate the chronic dietary exposure to Cr(III) in the age class ‘Other children’. The mean dietary exposure ranged from 1.6 μg/kg b.w. per day to 4.9 μg/kg b.w. per day (minimum LB and maximum UB, respectively). The 95 th percentile dietary EFSA Journal 2014;12(3):3595 50
Chromium in food and drinking water exposure estimates ranged from a minimum LB of 2.9 μg/kg b.w. per day to a maximum UB of 7.9 μg/kg b.w. per day. In general, the main contributors to the exposure in the age class ‘Other children’ were the food groups ‘Milk and dairy products’ (7-22 % of the total, median = 11 %), ‘Chocolate (Cocoa) products’ (4-32 % of the total, median =12 %) and ‘Bread and rolls’ (1-19 % of the total, median = 10 %) (Figure 12). Apart from the high contribution to the exposure of composite food in some countries, the food group ‘Vegetables and vegetable products (including fungi)’ contributed among the different dietary surveys only between 1 % to 10 % of the total exposure to Cr(III) (median = 4 %). As for ‘Toddlers’, the reported consumption of cocoa powder was responsible of the high contribution of ‘Non-alcoholic beverages’ in the two dietary surveys with the highest values (31 % and 40 %). NFA enKid NUT_INK05 VCP_kids EFSA_TEST INRAN_SCAI_2005_06 Regional_Crete DONALD_2008 DONALD_2007 DONALD_2006 INCA2 STRIP DIPP Danish_Dietary_Survey SISP04 NUTRICHILD Regional_Flanders 0 10 20 30 40 50 60 70 80 90 100 % Milk and dairy products Chocolate (Cocoa) products Bread and rolls Vegetables and vegetable products (including fungi) Composite food (including frozen products) Fruit and fruit products Meat and meat products (including edible offal) Animal and vegetable fats and oils Potatoes and potatoes products Snacks, desserts, and other foods Spices Sugar and confectionary (non chocolate products) Biscuits (cookies) Fish and other seafood (including amphibians, reptiles, snails and insects) Non-alcoholic beverages (excepting milk based beverages) Rest of food categories Figure 11: Main food groups contributing (%) to the chronic dietary exposure to Cr(III) for the age class ‘Other children’. Data are presented by individual dietary surveys across Europe using LB estimations. The names on the left refer to the names of the different surveys (see Appendix F for more details). 6.1.2.3. Adolescents A total of 12 dietary surveys were available to estimate the chronic exposure to Cr(III) in ‘Adolescents’. The minimum value for the mean dietary exposure at the LB was 0.9 μg/kg b.w. per day, while the maximum estimated value at the UB was 2.5 μg/kg b.w. per day. For the 95 th percentile dietary exposure the values ranged between 1.7 μg/kg b.w. per day (minimum LB) and 4.8 μg/kg b.w. per day (maximum UB). In general, the main foods contributing to the dietary exposure to Cr(III) in ‘Adolescents’ were the same as described for ‘Toddlers’. The main food groups were ‘Bread and rolls’ (6-20 % of the total, median = 13 %), ‘Chocolate (Cocoa) products’ (4-30 % of the total, median = 9 %) and ‘Milk and dairy products’ (6-17 % of the total, median 8 %). In addition, ‘Non-alcoholic beverages’ was also a major source of exposure to Cr(III) (1-37 % of the total, median 8 %) with an important contribution of cocoa powder used to prepared cocoa drinks (particularly in specific surveys such as enKid and EFSA Journal 2014;12(3):3595 51
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Chromium in <strong>food</strong> and <strong>drinking</strong> <strong>water</strong><br />
concentration of 2 g/L in human milk was selected. This selection was based on the upper value of<br />
the range of mean total Cr concentrations described among most of the European studies on breast<br />
milk samples, 0.14-1.80 µg/L (see Section 4.1.3 and Appendix D). The mean dietary exposure for an<br />
infant of 6.1 kg exclusively fed with human milk was estimated to be 0.3 g/kg b.w. per day, while for<br />
the same infant with high consumption the dietary exposure would be 0.4 g/kg b.w. per day.<br />
Nine dietary surveys were available for ‘Toddlers’. This age class showed the highest exposure to<br />
Cr(III). The mean dietary exposure to Cr(III) ranged from 2.3 μg/kg b.w. per day to 5.9 μg/kg b.w. per<br />
day (minimum LB and maximum UB across European dietary surveys, respectively). The<br />
95 th percentile dietary exposure estimates ranged from a minimum LB of 3.4 μg/kg b.w. per day to a<br />
maximum UB of 9.0 μg/kg b.w. per day.<br />
In the toddler population the exposure to Cr(III) was in general mainly due to ‘Foods for infants and<br />
small children’ (1-26 % of the total, median = 9 %), ‘Milk and dairy products’ (9-25 % of the total,<br />
median = 14 %), and ‘Bread and rolls’ (0.3-12 % of the total, median = 10 %) (Figure 10). In some<br />
dietary surveys ‘Chocolate (cocoa) products’ also made an important contribution to the dietary<br />
exposure to Cr(III). The contribution of the <strong>food</strong> group ‘Vegetables and vegetable products (including<br />
fungi)’ ranged between 3 % and 8 % of the total (median = 6 %). In one survey the reported<br />
consumption of cocoa powder led to the <strong>food</strong> group ‘Non-alcoholic beverages’ to contribute up to<br />
45 % of the total exposure to Cr(III). However, the consumption data from this dietary survey refers<br />
only to 17 individuals and, therefore, this value could not be representative.<br />
INRAN_SCAI_2005_06<br />
NUTRICHILD<br />
Milk and dairy products<br />
Food for infants and small children<br />
Bread and rolls<br />
enKid<br />
VCP_kids<br />
INRAN_SCAI_2005_06<br />
DONALD 2008<br />
DONALD 2007<br />
DONALD 2006<br />
DIPP<br />
NUTRICHILD<br />
Regional_Flanders<br />
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%<br />
%<br />
Chocolate (Cocoa) products<br />
Vegetables and vegetable products<br />
(including fungi)<br />
Fruit and fruit products<br />
Meat and meat products (including<br />
edible offal)<br />
Potatoes and potatoes products<br />
Sugar and confectionary (non chocolate<br />
products)<br />
Composite <strong>food</strong> (including frozen<br />
products)<br />
Animal and vegetable fats and oils<br />
Biscuits (cookies)<br />
Fish and other sea<strong>food</strong> (including<br />
amphibians, reptiles, snails and insects)<br />
Non-alcoholic beverages (excepting milk<br />
based beverages)<br />
Rest of <strong>food</strong> categories<br />
Figure 10: Main <strong>food</strong> groups contributing (%) to the chronic dietary exposure to Cr(III) for the age<br />
classes ‘Infants’ (from the top the two first surveys) and ‘Toddlers’. Data are presented by individual<br />
dietary surveys across Europe using LB estimations. The names on the left refer to the names of the<br />
different surveys (see Appendix F for more details).<br />
6.1.2.2. Other children<br />
A total of 17 dietary surveys were available to evaluate the chronic dietary exposure to Cr(III) in the<br />
age class ‘Other children’. The mean dietary exposure ranged from 1.6 μg/kg b.w. per day to<br />
4.9 μg/kg b.w. per day (minimum LB and maximum UB, respectively). The 95 th percentile dietary<br />
EFSA Journal 2014;12(3):3595 50