efsa-opinion-chromium-food-drinking-water

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Chromium in food and bottled water Table J23: MCH The benchmark dose (BMD -5 ), the 95 % benchmark dose lower confidence limit (BMDL -5 ) values for a BMR of 5 % decrease of weights (mg/10 g b.w.) relative to control for the selected model with characteristics of the model fit using PROAST. Selected model for dose-response analysis in bold. Models Converged N of parameters Loglikelihood EXPONENTIAL MODELS full 1 6 79.05 m1 1 2 34.57 m2 1 3 44.81 m3 1 4 59.94 m4 1 4 66.51 BMD 05 (mg/kg b.w. per day) BMDL 05 (mg/kg b.w. per day) m5 1 5 71.51 0.53 0.33 HILL MODELS full na 6 79.05 m1 1 2 34.57 m2 1 3 45.55 m3 1 4 55.26 m4 1 4 62.03 m5 1 5 71.15 0.62 0.49 b.w.: body weight; na: not applicable. Figure J23: Fit of Model fit for the Exponential (left) and the Hill (right) models EFSA Journal 2014;12(3):3595 256
Chromium in food and bottled water ABBREVIATIONS 8-OHdG AAS AFC Panel AI ANS Panel ALT AST ATSDR BCF BE BEC BG Bipea BMD BMDL 05 BMDL 10 BP BSO b.w. CAdSV CCA CCT CDPH CFA CHO CICAD CNS COM COMA CONTAM Panel Cr 2− Cr 2 O 7 Cr(III) Cr(OH) 3 8-hydroxy-2’-deoxyguanosine Atomic absorption spectrometry EFSA Panel on Food Additives Flavourings, Processing Aids and Materials in Contact with Food Adequate intake EFSA Panel on Food Additives and Nutrient Sources added to Food Alanine aminotransferase; Aspartate aminotransferase Agency for Toxic Substances and Disease Registry Bioconcentration factor Belgium Background equivalent concentration Bulgaria Bureau Interprofessionnel d'Etudes Analytiques Benchmark dose Lower 95 % confidence limit for a benchmark dose at 5 % extra risk Lower 95 % confidence limit for a benchmark response at 10 % extra risk Boiling point Buthionine sulfoximine Body weight Catalytic adsorptive stripping voltammetry Chromated copper arsenate Collision/reaction cell technology California Department of Public Health (former California Department of Health Services, CDHS) Continuous flow analysis Chinese hamster ovary Concise International Chemical Assessment Document Central nervous system Committee on Mutagenicity of Chemicals in Food (UK) Committee on Medical Aspects of Food Policy (UK) EFSA Panel on Contaminants in the Food Chain Chromium Dichromate ions Trivalent chromium Chromium trihydroxide EFSA Journal 2014;12(3):3595 257
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EFSA Journal 2014;12(3):3595 SCIENT
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Chromium in food and drinking water
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4.2.2.1. Data collection on food (e
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Sampling year Number of samples Chr
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Number of analtycal results Samplin
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4.2.4. Occurrence data by food cate
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7.2.1.4. Genotoxicity Chromium in f
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7.5. Dose-response assessment Chrom
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Human observations Chromium in food
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