efsa-opinion-chromium-food-drinking-water

Chromium in food and bottled water
Table J23:
MCH
The benchmark dose (BMD -5 ), the 95 % benchmark dose lower confidence limit (BMDL -5 ) values for a
BMR of 5 % decrease of weights (mg/10 g b.w.) relative to control for the selected model with
characteristics of the model fit using PROAST. Selected model for dose-response analysis in bold.
Models
Converged
N of
parameters
Loglikelihood
EXPONENTIAL MODELS
full 1 6 79.05
m1 1 2 34.57
m2 1 3 44.81
m3 1 4 59.94
m4 1 4 66.51
BMD 05
(mg/kg b.w.
per day)
BMDL 05
(mg/kg b.w.
per day)
m5 1 5 71.51 0.53 0.33
HILL MODELS
full na 6 79.05
m1 1 2 34.57
m2 1 3 45.55
m3 1 4 55.26
m4 1 4 62.03
m5 1 5 71.15 0.62 0.49
b.w.: body weight; na: not applicable.
Figure J23: Fit of Model fit for the Exponential (left) and the Hill (right) models
EFSA Journal 2014;12(3):3595 256