efsa-opinion-chromium-food-drinking-water

Chromium in food and bottled water
Table J.22: MCV
The benchmark dose (BMD 05 ) and the 95 % benchmark dose lower confidence limit (BMDL 05 ) values
are given for a BMR of 5 % decrease of weights (mg/10 g b.w.) relative to control with characteristics
of the model fit. The model with lowest BMDL 05 is highlighted in bold.
Models
Converged
N of
parameters
Loglikelihood
EXPONENTIAL MODELS
full 1 6 103.7
m1 1 2 36.22
m2 1 3 71.72
m3 1 4 86.01
m4 1 4 99.07
BMD 05
(mg/kg b.w.
per day)
BMDL 05
(mg/kg b.w.
per day)
m5 1 5 103.67 0.55 0.41
HILL MODELS
full na 6 103.07
m1 1 2 36.22
m2 1 3 74.33
m3 1 4 87.01
m4 1 4 95.51
m5 1 5 103.43 0.61 0.47
b.w.: body weight; na: not applicable.
Figure J22:
Fit of Model fit for the Exponential (left) and the Hill (right) model
EFSA Journal 2014;12(3):3595 255