2009 Pittcon Final Program - Pittcon Web Archives
2009 Pittcon Final Program - Pittcon Web Archives
2009 Pittcon Final Program - Pittcon Web Archives
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<strong>Pittcon</strong> <strong>2009</strong> Technical <strong>Program</strong><br />
1:35 (1420-1) Direct Observation of Atomic Arrangement of<br />
Surface by Holography and Stereo-Photography HIROSHI DAIMON, Nara<br />
Institute of Science and Technology (NAIST), Fumihiko Matsui, Tomohiro<br />
Matsushita<br />
2:10 (1420-2) In situ TEM and Multidimensional Electron<br />
Tomography on Nanostructured Materials XIAO FENG ZHANG, Hitachi<br />
High Technologies America, Konrad Jarausch<br />
2:45 (1420-3) An Electron Microscope for Nanotechnology: To See<br />
Something Small You'll Need Something Big MICHAEL MILLER KERSKER,<br />
JEOL USA<br />
3:20 (1420-4) Latest Developments in X-ray Photoelectron<br />
Spectroscopy and Their Application to Nanosurfaces DAVID SURMAN,<br />
Kratos Analytical Inc.<br />
3:55 (1420-5) The Future of Molecular Spectroscopy for the<br />
Advancement of Nanotechnology ADAM MATTHEW GILMORE, HORIBA<br />
WORKSHOP Session 1430<br />
Case Studies in the Stability of Drug Substances and Drug<br />
Products - arranged by Brian K Nunnally, Wyeth<br />
Tuesday Afternoon, Room S501d<br />
Brian K Nunnally, Wyeth, Presiding<br />
1:30 Introductory Remarks - Brian K Nunnally<br />
1:35 (1430-1) Stress Stability Studies for Protein Therapeutics: A<br />
Case Study JAMIE MR MOORE, Genentech<br />
2:10 (1430-2) A Case Study in Stability Study Design and<br />
Execution to Meet Complex Submission Requirements JEFFREY<br />
KETTLER, Wyeth<br />
2:45 (1430-3) Opportunities in Pharmaceutical Off-<br />
Shoring/Outsourcing BARRY JAY SCHEER, Bristol-Myers Squibb, Pankaj<br />
Shah, Jingpin Jia, Kalpana Chaturvedi<br />
3:20 (1430-4) Following the Stability of a Clinical Vaccine Through<br />
its Intermediates, Drug Substance and Drug Product BRIAN K NUNNALLY,<br />
Wyeth<br />
3:55 Panel Discussion<br />
WORKSHOP Session 1440<br />
Your Questions Answered about Certified Reference Materials -<br />
arranged by Thomas J Mancuso and Ralph Obenauf, SPEX CertiPrep Group<br />
Tuesday Afternoon, Room S501bc<br />
Thomas J Mancuso, SPEX CertiPrep Group LLC, Presiding<br />
1:30 Introductory Remarks - Thomas J Mancuso and<br />
Ralph Obenauf<br />
1:35 (1440-1) A Stable Sulfide Standard: An Alternative to Zinc<br />
Acetate Preservation MARK HAMMERSLA, NSI Solutions<br />
2:05 (1440-2) Reference Materials (Certified or Not) for the<br />
Pharmaceutical Industry WILLIAM F KOCH, US Pharmacopeia, Johanna M<br />
Smeller<br />
2:35 (1440-3) Preparation of Reference Materials in the Food<br />
Testing Industry CURTIS JAMES WOOD, ERA<br />
3:05 Recess<br />
3:20 (1440-4) The Need, Use and Implementation of Traceability<br />
and Uncertainty Measurements in an Analytical Testing Laboratory<br />
LANCE BOYNTON, Absolute Standards, Inc.<br />
3:50 (1440-5) Relevance of ISO 17025 and ISO Guide 34 to<br />
Chemical Reference Materials Manufacturers THOMAS J MANCUSO, SPEX<br />
CertiPrep Group<br />
4:20 Panel Discussion<br />
ORGANIZED CONTRIBUTED<br />
Session 1450<br />
SESSION<br />
Analytical Diagnostics of Disease from Cellular Signals -<br />
arranged by Anna Brajter-Toth, University of Florida<br />
Tuesday Afternoon, Room S405a<br />
Anna Brajter-Toth, University of Florida, Presiding<br />
1:30 (1450-1) Monitoring Apoptosis Induction and Inhibition by<br />
Intracellular Multi-Parameter Fluorescence DIMITRI PAPPAS, Texas Tech<br />
University<br />
1:50 (1450-2) Analysis of Single Cells by Microseparation Methods<br />
NANCY ALLBRITTON, University of North Carolina, Chris Sims, Sumith<br />
Kottegoda<br />
2:10 (1450-3) Detecting Metabolic Rearrangements in Diseased<br />
Tissues Using Capillary LC-MS ROBERT T KENNEDY, University of<br />
Michigan<br />
2:30 (1450-4) Microfluidics: Enabling Diagnostics via Cellular<br />
Analysis DANA SPENCE, Michigan State University<br />
2:50 Recess<br />
3:05 (1450-5) Mapping Receptors on Cancer Cell Surface<br />
WEIHONG TAN, University of Florida, Yan Chen, Michael Mavros<br />
3:25 (1450-6) Electrocatalytic Detection of Cancer Biomarkers<br />
using Nanostructured Microelectrodes SHANA O KELLEY, University of<br />
Toronto<br />
3:45 (1450-7) Elucidating Cancer Cell Metabolism using Scanning<br />
Electrochemical Microscopy and Microfluidic Physiometry DAVID<br />
CLIFFEL, Vanderbilt University, Jeremy Wilburn, Madalina Ciobanu<br />
4:05 (1450-8) Metabolic Biomarkers of Cellular Oxidative Stress<br />
ANNA BRAJTER-TOTH, University of Florida, Mehjabin Kathiwala, Sergey<br />
Zharikov<br />
ORGANIZED CONTRIBUTED<br />
Session 1460<br />
SESSION<br />
Emerging Applications and Technologies for the Identification<br />
of Genotoxic Impurities - arranged by Arindam Roy, Covidien and Mike<br />
S Lee, Milestone Development Services<br />
Tuesday Afternoon, Room S404d<br />
Mike S Lee, Milestone Development Services, Presiding<br />
1:30 (1460-1) Business Impact of FDA Structural Alerts DAVID<br />
WAYNE BERBERICH, Covidien<br />
1:50 (1460-2) Detection of Trace Level Genotoxic Impurities in<br />
Early Phase Pharmaceutical Development using LC-MS and GC-MS<br />
Techniques DAVID ROBBINS, Eli Lilly and Company<br />
2:10 (1460-3) Impurities: Finding and Defining the Uninvited<br />
Guests ROBERT IAN ELLIS, Applied Biosystems/MDS Analytical<br />
Technologies, Alina Dindyal-Popescu, Tanya Gamble<br />
2:30 (1460-4) Identification and Characterization of a Novel<br />
Delivery Molecule for a Clandestine PDE-5 Inhibitor Drug in a Dietary<br />
Supplement by LC-MS n , FT-MS and NMR JAMES NEAL-KABABICK, Flora<br />
Research Laboratories, Ed George<br />
2:50 Recess<br />
3:05 (1460-5) Nanospray Ionization MS for the Analysis of Related<br />
Chemical Species in Complex Matricies: Investigation of Equimolar<br />
Response and Extended Dynamic Range GARY A VALASKOVIC, New<br />
Objective Inc.<br />
3:25 (1460-6) Case Study: Development of Highly Sensitive<br />
Analytical Method to Determine Low ppm Level of Genotoxic Impurities in<br />
Organic Synthesis Processes JIE ZHENG, Abbott Laboratories, Wayne A<br />
Pritts, Shuhong Zhang, Steve Wittenberger<br />
3:45 (1460-7) Evaluation of the Importance of Ionization Efficiency,<br />
Ion Transmission and Sensitivity for Impurity Profiling Applications using<br />
Multistage Mass Spectrometry DAVID A WEIL, Agilent Technologies<br />
4:05 (1460-8) Rapid Determination of Impurities utilizing Direct<br />
Analysis in Real Time (DART) Mass Spectrometry with Activated Surfaces<br />
BRIAN MUSSELMAN, IonSense, Inc., Elizabeth Crawford, Robert Cody<br />
Tuesday, p.m., March 10<br />
95