2009 Pittcon Final Program - Pittcon Web Archives

Conferee Networking Sessions
HPLC of Soluble and Membrane Proteins
Facilitator: Dr. Mark Chiu, Abbott Laboratories………………………………………………………………Room N427D
There is increased demand for better characterizations of proteins used for assays, structure determination,
antigens for antibody/binding protein generation, and therapeutic reagents. Since proteins are labile and obtained
in small quantities, HPLC combined with various on-line detection systems can perform rapid, sensitive, and
quantitative characterizations of protein activity, conformation, and associations. We will discuss on-going
problems of protein characterization as well as potential frontiers to address the biochemistry of proteins in cells
and tissues.
Monday, March 9, 2009, 1:30 – 3:30 p.m.
Outsourcing in the Pharmaceutical Industry
Facilitator: Mr. Brian P. Axe, Eli Lilly & Co. ……………………………………………………………………Room N426A
This Conferee Networking Session has been suggested in order to discuss topics relating to outsourcing in the
Pharmaceutical Industry. The goal of this session is for conferees to establish an outsourcing network among
various colleagues in the industry and share common experiences. Discussion topics during the session could
include:
• Outsourcing/In-Sourcing/Off-Shoring
• Outsourcing in our current environment – Where are we headed?
• Shared experiences of outsourcing - Successes/Failures
• Establishing a partnership – What does it take?
• Information Sharing with third parties
• Data transfer
• Quality oversight
High Throughput Analysis in the Pharmaceutical Field
Facilitator: Perry G. Wang, PhD, U.S. FDA ……………………………………………………………………Room N426B
Reducing timeline is one of the most important concerns for drug discovery and development, which have brought
about the need for high-throughput analytical approaches. It has proven that the throughput can be significantly
improved by using automated sample preparation and LC/MS/MS. Combination of automated 96-well (even 384-
well) sample preparation with the application of liquid chromatography coupled with tandem mass spectrometry
(LC/MS/MS) has enabled bioanalysts to face the high-throughput challenges
This session will discuss the automated sample preparation technique based on the use of 96-well and 384-well
format for extraction with a robotic liquid handling system and the application of these techniques to LC-MS and
LC-MS-MS, which has become an essential tool for drug discovery and development in the pharmaceutical industry
and biotechnology.
Energy Efficiency and Energy Conservation in the Workplace
Facilitator: Margaret M. Hall, PA Department of Environmental Protection………………Room N426C
This brainstorming session will foster an open exchange of ideas on what entities are presently doing or could be
doing to use less energy or to use energy more efficiently. Opportunities to save energy and thereby money are
everywhere. Share your ideas and learn what others are doing toward this important and timely topic.
Is High Pressure LC and the Related Equipment Necessary in Future LC Methodology
Facilitator: Mary Ellen P. McNally, DuPont Crop Protection,
Co-Facilitator: William J. Long, Ph.D., Agilent Technologies, Inc. …………………………… Room N427A
This networking session is directed to the practicing chromatographer or lab manager who would like to discuss the
direction of LC instrumentation in their laboratory. We are interested in hearing from successful laboratories that
might be using some state of the art technologies. We hope to include practioners with feedback on the following
topics: high temperature LC, automated method development techniques, column-switching utilization, high
pressure applications, fused core and small particle columns.
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