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CHLOROTHALONIL - 71 - APPENDIX IIIA List of studies 19 January 2005 Annex point/ refere nce numb er IIA, 5.4 IIA, 5.4 IIA, 5.8 Author(s) Proudlock, R.J., Greer, J.V., Elmore, E.A. Proudlock, R.J., Elmore, E.A. Savides, M. C., Marciniszy n, J. P., Killeen, J.C., Jr. Yea r 199 5 199 2 199 0 Title Source (where different from company) Company, Report No. GLP or GEP status (where relevant) Published or not In vivo bone marrow chromosomal analysis in Chinese Hamsters following multiple dose administration of technical chlorothalonil. Generated by: Ricerca Inc. Submitted by: Zeneca Agrochemicals Report no.: 6005-94-0047-TX-003 Date: 2 June 1995 GLP, Unpublished Chlorothalonil: Mouse micronucleus test Generated by: Huntingdon Research Centre Ltd Submitted by: Vischim S.R.L. Company file no.: VCM 27/920705 date: 08 September 1992 GLP, Unpublished Pharmacokinetic study to determine the effects of dose level on the metabolism of 14C-SDS-46851 by rats. Generated by: Ricerca, Inc. Submitted by: Zeneca Agrochemicals Report no.: 3043-88-0056-AM-001 Date: July 11, 1990c GLP, Unpublished

CHLOROTHALONIL - 72 - APPENDIX IIIA List of studies 19 January 2005 Annex point/ refere nce numb er IIA, 5.1 IIA, 5.1 Author(s) Savides, M. C., Marciniszy n, J. R., Killeen, J. C., Jr. Savides, M. C., Marciniszy n, J. P., Killeen, J. C., Jr. Yea r 199 0 199 0 Title Source (where different from company) Company, Report No. GLP or GEP status (where relevant) Published or not Study of urinary excretion of radiolabel by catheterized dogs following oral administration of 14C-chlorothalonil by gavage. Generated by: Ricerca, Inc. Submitted by: Zeneca Agrochemicals Report no.: 3086-89-0041-AM-001 Date: April 17, 1990a GLP, Unpublished Study to evaluate the urinary metabolites of chlorothalonil from male rhesus monkeys. Generated by: Ricerca, Inc. Submitted by: Zeneca Agrochemicals Report no.: 3349-89-0179-AM-001 Date: April 16, 1990b. GLP, Unpublished

CHLOROTHALONIL<br />

- 72 -<br />

APPENDIX IIIA<br />

List of studies<br />

19 January 2005<br />

Annex<br />

point/<br />

refere<br />

nce<br />

numb<br />

er<br />

IIA,<br />

5.1<br />

IIA,<br />

5.1<br />

Auth<strong>or</strong>(s)<br />

Savides, M.<br />

C.,<br />

Marciniszy<br />

n, J. R.,<br />

Killeen, J.<br />

C., Jr.<br />

Savides, M.<br />

C.,<br />

Marciniszy<br />

n, J. P.,<br />

Killeen, J.<br />

C., Jr.<br />

Yea<br />

r<br />

199<br />

0<br />

199<br />

0<br />

Title<br />

Source (where different from<br />

company)<br />

Company, Rep<strong>or</strong>t No.<br />

GLP <strong>or</strong> GEP status (where relevant)<br />

<strong>Published</strong> <strong>or</strong> <strong>not</strong><br />

Study of urinary excretion of<br />

radiolabel by<br />

catheterized dogs following <strong>or</strong>al<br />

administration<br />

of 14C-chl<strong>or</strong>othalonil by gavage.<br />

Generated by: Ricerca, Inc.<br />

Submitted by: Zeneca<br />

Agrochemicals<br />

Rep<strong>or</strong>t no.: 3086-89-0041-AM-001<br />

Date: April 17, 1990a<br />

GLP, Unpublished<br />

Study to evaluate the urinary<br />

metabolites of<br />

chl<strong>or</strong>othalonil from male rhesus<br />

monkeys.<br />

Generated by: Ricerca, Inc.<br />

Submitted by: Zeneca<br />

Agrochemicals<br />

Rep<strong>or</strong>t no.: 3349-89-0179-AM-001<br />

Date: April 16, 1990b.<br />

GLP, Unpublished

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