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CHLOROTHALONIL - 27 - APPENDIX II END POINTS AND RELATED INFORMATION 3. Ecotoxicology 20 December 2004 Bioconcentration Bioconcentration factor (BCF) Annex VI Trigger for the bioconcentration factor Clearance time (CT 50 ) (CT 90 ) 2300 l/kg based on r.a. In the fish BCF study r.a. in fish consisted of large number of components, only two were >10% of applied (whole fish based): di- and triglutathione conjugates, 18% and 12% of total r.a. residue. Metabolite SDS-3701 was detected as a minor component, and no unmetabolised chlorothalonil was detected. The BCF for chlorothalonil is estimated 40 µg/bee >63 µg/bee Other arthropod species Laboratory tests type crop type species tested Bravo 500 Bravo 720SC [kg a.i./ha] Dosage 2.2 [l/ha] Dosage a: 0.173 Dosage b: 6.0 Dosage c: 7.7 Dosage d: 10.5 Predacio base Typhlodro Dosage b:
CHLOROTHALONIL - 28 - APPENDIX II END POINTS AND RELATED INFORMATION 3. Ecotoxicology 20 December 2004 us mite set mus pyri moderately harmful (94% effect) Aphid parasitoi de base set Aphidius rhopalosiph i Aphidius spp. Dosage a, b and c: slightly harmful (41-62% effect) ground dwelling predator leaf dwelling predator Aleochara bilineata or Poecilus cupreus Chrysoperl a carnea Extended laboratory tests Predacio Typhlodro us mite mus pyri harmles s Dosage d: harmless Dosage c: harmless Dosage Mortality Fecundity* (kg as/ha) (%) 1.50 0 5.0 1.88 0 4.6 5.63 9 3.8 12.0 17 4.4 18.75 13 3.1 control 8.6 There were significant effects on fecundity at every dose, so the NOER < 1.50 kg as/ha. * mean number of eggs per female (7 – 14 DAT)
Page 1 and 2: EUROPEAN COMMISSION HEALTH & CONSUM
Page 3 and 4: - 3 - By letter 6 March 1998 Zeneca
Page 5 and 6: - 5 - Annex I to Directive 91/414/E
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