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CHLOROTHALONIL<br />

3 Ecotoxicology<br />

Terrestrial Vertebrates<br />

- 22 -<br />

APPENDIX II<br />

END POINTS AND RELATED INFORMATION<br />

3. Ecotoxicology<br />

20 December 2004<br />

Acute toxicity to mammals:<br />

Acute toxicity to birds:<br />

Dietary toxicity to birds:<br />

Reproductive toxicity to birds:<br />

Long term toxicity to<br />

mammals:<br />

chl<strong>or</strong>othalonil LD50 >5000 mg/kg<br />

bw<br />

SDS-3701 LD50 242 mg/kg bw<br />

chl<strong>or</strong>othalonil LD50 >2000 mg/kg<br />

bw<br />

SDS-3701 LD50 158 mg/kg bw<br />

chl<strong>or</strong>othalonil LC50 >5200 mg/kg<br />

fd<br />

SDS-3701 LC50 1780 mg/kg fd<br />

chl<strong>or</strong>othalonil NOEC 160 mg/kg<br />

fd<br />

SDS-3701 NOEC 50 mg/kg fd<br />

chl<strong>or</strong>othalonil NOEC 330 mg/kg<br />

fd (developmental NOAEL)<br />

SDS-3701 NOEC 30 mg/kg fd<br />

(reproductive NOAEL (decreased<br />

body weight pups))<br />

Aquatic Organisms<br />

Acute toxicity<br />

Species time effect value<br />

mg<br />

a.i./L<br />

Onc<strong>or</strong>hynchus<br />

mykiss<br />

LC50 0.038 geometric<br />

mean<br />

Lepomis macrochirus LC50 0.052 geometric<br />

mean<br />

Cyprinus carpio LC50 0.076 geometric<br />

mean<br />

Ictalurus punctatus 96 LC50 0.047

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