EU-SICHERHEITSDATENBLATT Dieselkraftstoff ... - Schmierstoffe

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Vacuum Gas Oils, Hydrocracked Gas Oils, and Distillate Fuels REFERENCES Anderson, J. Neff, J. Cox, B. Tatem, H and Hightower, G (1974). Characteristics of dispersions and water-soluble extracts of crude and refined oils and their toxicity to estuarine crustaceans and fish. Marine Biology 27, 75-88. Anon (2003). High production volume (HPV) chemical challenge program. Test plan Gas Oils Category. American Petroleum Institute. Report no.: 201-14835. API (1978). Mutagenicity evaluation of diesel fuel. Testing laboratory: Litton Bionetics Inc. American Petroleum Institute. Med. Res. Pub. 26-60102 API (1979). In-vitro and in-vivo mutagenicity studies No. 2 Home heating oil sample API 78-4 API Report No. 27-30140 API (1979a). Teratology study in rats, diesel fuel, final report. Testing laboratory: Litton Bionetics, Inc. Kensington, Maryland. Report no.: 20698-11. Owner company: American Petroleum Institute, Washington, D. C. Study number: 27-32174. Report date: 1979-03-21. API (1979b). Inhalation/teratology study in rats- fuel oil. Testing laboratory: Litton Bionetics, Inc, Kensington, Maryland. Report no.: 21035-03. Owner company: American Petroleum Institute, Washington DC. Study number: 27-30483. Report date: 1979-09-17. API (1980aa). Acute toxicity tests. API 78-2 (No. 2 Home heating oil (30% cat)). Primary dermal irritation. Primary eye irritation. Skin sensitization. Acute dermal toxicity. Acute oral toxicity. Subacute dermal toxicity. Testing laboratory: Elars Bioresearch Laboratories Inc. Owner company: American Petroleum Institute. Report No. 27-32771. API (1980bb). Acute toxicity tests. API 78-3 (No. 2 Home heating oil (10% cat)). Primary dermal irritation. Primary eye irritation. Skin sensitization. Acute dermal toxicity. Acute oral toxicity. Subacute dermal toxicity. Testing laboratory: Elars Bioresearch Laboratories Inc. Owner company: American Petroleum Institute. Report No. 27-32773. API (1980cc). Mutagenicity evaluation of diesel fuel in the mouse dominant lethal assay. API Medical research publication 28-31346 API (1980a). Acute Toxicity Tests API #78-4 #2 home heating oil (50% cat). Testing laboratory: Elars Bioresearch Laboratory, Fort Collins, CO. Report no.: 27-32068. Owner company: American Petroleum Institute, Washington DC. Study number: 1443. Report date: 1980-07-17. API (1980b). Acute Toxicity Tests API #79-6 diesel fuel (marketplace sample). Testing laboratory: Elars Bioresearch Laboratories, Inc., Fort Collins, CO. Report no.: 27-32817. Owner company: American Petroleum Institute, Washington DC. Study number: 1443. Report date: 1980-09-02. API (1982a). Acute oral toxicity study in rats. Acute dermal toxicity study in rabbits. Primary dermal irritation study in rabbits. Primary eye irritation study in rabbits. API 81-09 (Hydrodesulphurised Middle Distillate). Testing laboratory: Hazleton Raltech Inc. Owner company: American Petroleum Institute. Report No. 30-32347. API (1982b). Acute oral toxicity study in rats. Acute dermal toxicity study in rabbits. Primary dermal irritation study in rabbits. Primary eye irritation study in rabbits. API 81-09 (Hydrodesulphurised Middle Distillate). Testing laboratory: Hazleton Raltech Inc. Owner company: American Petroleum Institute. Report No. 30-32348. API (1983c). 28-day dermal toxicity study in the rabbit. API 81-09 (Hydrodesulphurised Middle Distillate). Testing laboratory: Borriston Laboratories Inc. Owner company: American Petroleum Institute. Report No. 30-32298. API (1983d). 28-day dermal toxicity study in the rabbit. API 81-10 (Hydrodesulphurised Middle Distillate. Testing laboratory: Borriston Laboratories Inc. Owner company: American Petroleum 2010-07-30 CSR 187
Vacuum Gas Oils, Hydrocracked Gas Oils, and Distillate Fuels Institute. Report No. 30-32296. API (1983a). LC50 acute inhalation toxicity evaluation of a petroleum-derived hydrocarbon in rats. API 81-09 (Hydrodesulphurised Middle Distillate). Testing laboratory: International Research and Development Corporation. Owner company: American Petroleum Institute. Report No. 30-32856. API (1983b). LC50 acute inhalation toxicity evaluation of a petroleum-derived hydrocarbon in rats. API 81-10 (Hydrodesulphurised Middle Distillate). Testing laboratory: International Research and Development Corporation. Owner company: American Petroleum Institute. Report No. 30-32857. API (1984a). Dermal sensitisation study in guinea pigs, closed patch technique. API 81-09 (Hydrodesulphurised Middle Distillate). Testing laboratory: Hazleton Laboratories America Inc. Owner company: American Petroleum Institute. Report No. 31-31352. API (1984b). Dermal sensitisation study in guinea pigs, closed patch technique. API 81-10 (Hydrodesulphurised Middle Distillate). Testing laboratory: Hazleton Laboratories America Inc. Owner company: American Petroleum Institute. Report No. 31-31414. API (1984c). Mutagenicity evaluation in the rat bone marrow cytogenetic assay and the mouse lymphoma forward mutation assay, API 81-10 (Hydrodesulphurised Middle Distillate. Testing laboratory: Litton Bionetics. Owner company: American Petroleum Institute. Report No. 32-30535. API (1985a). Acute in vivo cytogenetics assay in male and female rats. Testing laboratory: Microbiological Associates, Inc., Bethesda, Maryland. Report no.: T2419.105001. Owner company: American Petroleum Institute. Study number: 32-32408. Report date: 1985-05-30. API (1985b). Acute toxicity studies: hydrodesulphurized middle distillate, Sample 81-09. Testing laboratory: Hazleton Raltech. Owner company: American Petroleum Institute. Report No. 30-32347. API (1985c). Acute toxicity studies: Hydrodesulphurized Middle Distillate, Sample 81-10. Testing laboratory: Hazleton Raltech. Owner company: American Petroleum Institute. Report No. 30-32348. API (1985d). Mutagenicity evaluation study in the rat bone marrow cytogenetic assay and the mouse lymphoma forward mutation assay. API 81-09 (Hydrodesulphurised Middle Distillate). Testing laboratory: Litton Bionetics. Owner company: American Petroleum Institute. Report No. 32-30965. API (1986a). Four week subchronic inhalation toxicity study in rats. Final report. API 81-07 hydrodesulfurized kerosine (petroleum) (CAS 64742-81-0). API 81-09 hydrodesulfurized middle distillate (petroleum) (CAS 64742-80-9). API 81-10 hydrodesulfurized middle distillate (petroleum) (CAS 64742-80-9). American Petroleum Institute HESD Pub. 33-32724. API (1986b). Mutagenicity in a mouse lymphoma mutation assay, API 81-10, hydrodesulphurised middle distillate, CAS No. 64742-80-9. Testing laboratory: Litton Bionetics, Kensington, Maryland. Report no.: 20989. Owner company: American Petroleum Institute, Washington, DC. Study number: 33-31224. API (1987a). Mutagenicity of API 81-10 (ARO aromatic fraction of Hydrodesulphurised Middle Distillate), CAS No. 64742-80-9, (coded as API 86-10 ARO), in a mouse lymphoma mutation assay. Testing laboratory: Hazleton Biotechnologies Company. Owner company: American Petroleum Institute. Report No. 34-32644. API (1987b). Mutagenicity of API 81-10 (Hydrodesulphurised Middle Distillate), CAS No. 64742-80-9 (coded as 86-10), in a mouse lymphoma mutation assay. Testing laboratory: Hazleton Laboratories America Inc. Owner company: American Petroleum Institute. Report No. 34-32643. API (1987c). Mutagenicity of API 81-10 SAT saturated fraction of Hydrodesulphurised Middle Distillate, CAS No. 64742-80-9 (coded as API 86-10 SAT), in a mouse lymphoma mutation assay. Testing laboratory: Hazelton Biotechnologies Company. Owner company: American Petroleum Institute. Report No. 34-32645. API (1988). Sister chromatid exchange assay in chinese hamster ovary (CHO) cells. Testing laboratory: Microbiological Associates, Inc., Bethesda, Maryland. Report no.: T5338.334006. Owner 2010-07-30 CSR 188
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EU-SICHERHEITSDATENBLATT gemäß Ve
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Vacuum Gas Oils, Hydrocracked Gas O
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Page 43 and 44: Vacuum Gas Oils, Hydrocracked Gas O
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Page 127 and 128: Combined Professional - Manual spra
Page 129 and 130: Industrial - Bulk transfers CS14 Da
Page 131 and 132: Professional - Maintenance and CS77
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Page 135 and 136: Professional - Treatment and dispos
Page 137 and 138: Industrial - operation of open CS16
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Gas Oils (Vacuum) 4 DNEL (inhalatio
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Industrial - Tabletting, CS100 Indo
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Combined Professional - Manual spra
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Industrial - Bulk transfers CS14 Da
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Professional - Maintenance and CS77
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Note: differentiated Industrial -SU
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Professional - Treatment and dispos
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Industrial - operation of open CS16
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This tool is provided for informati
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An Evaluation of the Persistence, B
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Table of Contents Executive Summary
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2.0 Outline of PBT/vPvB Assessment
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3.0 Persistence Assessment of Petro
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100.0 Half-life predicted (days) 10
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2,3-dimethylheptane 9 7.7 6.2 7.4 2
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ioHCwin half-life (days) 10000.0 10
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criterion. It can be concluded that
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Hydrocarbon C nr BioHCwin Predicted
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ioHCwin half-life (days) 1000000.0
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Hydrocarbon C nr BioHCwin Predicted
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enzo[a]pyrene 20 421.6 16.5 Table 1
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(see Appendix 2). Since BCF predict
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10000 BCF (Arnot) 1000 100 10 1 n-P
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exhibit BMFs near unity (Figure 28)
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2,2,4,4,6,8,8- heptamethyl nonane 1
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Hydrocarbon C BMF BCF (Arnot) Dieta
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BCF (regression) 100000 10000 1000
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4.5 Polynaphthenic hydrocarbons Reg
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Experimental BMF 10 1 Polynaphth. D
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enzene n-octylbenzene 14 0.034 403
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10000 1000 BCF (Arnot) 100 10 1 NMA
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and appears to be an outlier. This
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4-ethylbiphenyl 14 863 1039 C Yakat
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100000 BCF (regression) 10000 1000
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10 Experimental BMF 1 0.1 NDiAr Die
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Hydrocarbon C BMF Arnot BCF Dietary
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Hydrocarbon C BMF Arnot BCF Dietary
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Acenaphthene Acenaphthylene Benz(a)
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5.0 Summary of Persistence and Bioa
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lower water solubility, it is possi
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properties of petroleum hydrocarbon
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8.0 References Anonymous (2004). Fi
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EMBSI (2007c). Fish, dietary bioacc
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Prince RC, Walters CC. (2007). Biod
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Appendix 1. Hydrocarbon structures
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iP 14 2,4,10-Trimethylundecane CC(C
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MN 7 1,2-Dimethylcyclopentane CC1C(
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MN 14 n-Nonylcyclopentane CCCCCCCCC
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MN 29 MN 29 MN 30 n-Tetracosylcyclo
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hexahydroindane DN 20 2,4-dimethylo
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PN 27 Phenanthrene 2,6-dimethylhept
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MAr 13 1-Methyl-3-hexylbenzene Cc1c
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NMAr 12 n-Propylindan c1ccc2CC(CCC)
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NMAr 24 c1cc(CC(C)CCCC(C)CCCCC)c2CC
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NMAr 29 NMAr 29 NMAr 29 NMAr 29 NMA
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DAr 16 2-Hexylnaphthalene CCCCCCc1c
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NDAr 16 n-Butylacenaphthene c12cccc
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NDAr 26 Dimethyloctyl-1,2,3,6,7,8-
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PAr 19 Ethylbenzo(a)fluorene C3c1cc
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PAr 22 n-Pentylbenzo(a)fluorene C3c
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PAr 28 Isohexyl-octadecahydro-picen
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Appendix 3. CONCAWE Position Paper
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probabilities are adjusted to best
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1.2.2 OASIS LMC Models: Toxicologic
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environmental chemicals (database o
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dihydrodiol. These dihydroxylated i
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Table 1 : PBT assessment of C15 str
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1: The following structures were pr
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Dimitrov SD, Dimitrova N, Mekenyan
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hydrocarbons and azaarenes original
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Verhaar HJM, van Leeuwen CJ, Hermen
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CONCAWE AQUATIC TOXICITY PREDICTION
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CONTENTS (Continued) Section Page 1
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1-2 The model predictions include m
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2-1 SECTION 2 2 SUMMARY OF COMPOSIT
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10-1 SECTION 10 10 SUMMARY OF COMPO
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