XXII. BIOCHEMICKÝ ZJAZD - Jesseniova lekárska fakulta

Posters
1.
LABOraTORY BIOMarKERS IN ISCHEMIC STROKE AND
DEPRESSION IN HUMAN PATIENTS
Daniel Čierny 1 , Stanislav Celec 1 , Mária Kovalská 1 , Peter Kaplán 1 , Igor Ondrejka 2 ,
Egon Kurča 3 and Ján Lehotský 1
1
Department of Medical Biochemistry, 2 Psychiatric clinic, 2 Neurological clinic,
Jessenius Fac Med, Comenius University, Martin, 03601, Slovakia
Due to the extreme complex pathogenesis of ischemic stroke, prognostic value of
laboratory parameters is still matter of debate. A number of brain biomarkers for the
diagnosis of ischemic stroke have been evaluated for clinical use in the past several
years. Neurobiological basis of depression is not yet clarified and it is not yet clear the
etipathogenesis of poststroke occurred depression. We present here laboratory examinations
of plasma derievd analytes in the group of ischemic stroke patients, in the group
of patients with depression compared with the group of apparently healthy subjects.
Laboratory results indicate for a time dependent association between ischemic damage
and biochemical parameters in postischemic plasma. It also suggests for their use as an
additional predictors of tissue damage progression.
Supported by: VEGA 0049/09, COST B30, VVCE 0064/07, MZ 2007/55UK-16.
XXII. Biochemistry Congress, Martin
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