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Integrating MEG, EEG and fMRI data

Integrating MEG, EEG and fMRI data

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Results<br />

motor strong motor weak painful<br />

I 1 I 5<br />

I 9<br />

SI - increase in amplitude from I1 to I5, then saturation: increasing<br />

synchronization mechanism of post-synaptic potentials, then “ceiling” effect on the<br />

involved myelinated Aβ fibers (nociceptive innervation in SI mainly represented by<br />

much slower Aδ <strong>and</strong> C unmyelinated fibres)<br />

SII - decrease for strong motor stimulation: “gating” effect due to the poor<br />

nociceptive specificity of the electrical stimulation involving possible interference<br />

in the evoked activation of the “non painful” <strong>and</strong> “painful” populations; increase for<br />

weak painful stim.: stronger attention to the stimulus, <strong>and</strong> amount of activated “non<br />

painful” neurons decreasing with the “gating” effect<br />

•Possible existence of two adjacent neuronal pools indistinguishable by <strong>MEG</strong>

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