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Integrating MEG, EEG and fMRI data

Integrating MEG, EEG and fMRI data

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How can we integrate <strong>MEG</strong>, <strong>EEG</strong>, <strong>and</strong> <strong>fMRI</strong> ?<br />

c. Use of distributed sources <strong>and</strong> regularization of<br />

Linear inverse Estimation (LE)<br />

• The solution of the <strong>MEG</strong> (<strong>EEG</strong>) inverse problem<br />

with a distributed source model requires the<br />

solution of a linear equation such as:<br />

Ax – b = 0<br />

where A is the lead field matrix:<br />

# rows = # field (or potential) measurements (knowns)<br />

# columns = # dipole components (unknowns)<br />

x is a column vector of dipole components<br />

b is a column vector of measured field components<br />

(for a review, see: Del Gratta et al., Reports on Progress in Physics, 2001)

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