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Farmacologie van de inhalatie-anesthetica

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Sevoflurane: hemodynamica<br />

• vermin<strong>de</strong>ring contractiliteit als isoflurane<br />

• daling SVR min<strong>de</strong>r groot dan isoflurane<br />

• polsfrequentie veran<strong>de</strong>rt weinig<br />

• geen adrenerge stimulatie bij snelle concentratiestijging, geen<br />

sensitisatie voor catecholamines<br />

• vermin<strong>de</strong>ring myocard VO2, coronair dilatatie, geen steal<br />

Circulatoire effecten<br />

BP<br />

halo enfl isofl <strong>de</strong>sfl sevo<br />

HR<br />

NC<br />

NC<br />

NC<br />

SVR<br />

NC<br />

CO<br />

NC<br />

NC

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