Farmacologie van de inhalatie-anesthetica
Farmacologie van de inhalatie-anesthetica
Farmacologie van de inhalatie-anesthetica
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Nitrous oxi<strong>de</strong><br />
• 30 maal meer oplosbaar in bloed dan stikstof: diffusie naar<br />
luchthou<strong>de</strong>n<strong>de</strong> holten met volume-expansie of drukstijging:<br />
gasembolen, pneumo-encephalon, pneumothorax, darmen,<br />
mid<strong>de</strong>noor…<br />
• Volume of pneumothorax will double in 10 min when 70 % N2O<br />
is given<br />
• Stop immediately with N2O administration if air embolism<br />
occurs<br />
• Beware with the use of N2O in cavity surgery<br />
• Nitrous oxi<strong>de</strong> and intra-ocular gas !!!!!<br />
• Nitrous oxi<strong>de</strong> and endoscopic surgery in general : combustion ?<br />
( N2O for establishing e.g. pneumoperitoneum )
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