COSIG CONFERENCE BROCHURE.pdf - Drexel University College ...
COSIG CONFERENCE BROCHURE.pdf - Drexel University College ... COSIG CONFERENCE BROCHURE.pdf - Drexel University College ...
COSIG Co-Occurring Disorders Conference, Hershey PA, May 15-17, 2006 Alcohol Diffuses to the Fetus during Gestation and in Breast Milk during Breastfeeding Placenta Umbilical arteries and veins Umbilical cord Heart The facial features of FAS in mouse fetus that was exposed to single binge of alcohol during 1 st trimester. Dysmorphic Features Seen in Individuals with Prenatal Alcohol Exposure child with FAS Narrow forehead mouse fetus Short palpebral fissures Small nose Small midface Thin upper lip with flattened philtrum alcohol-exposed normal Early Identification of Fetal Alcohol Syndrome leads to improved outcome Examples of dysmorphic features in older Individuals with FASD (FAS) • Small palprebral fissures • Smooth philtrum • This upper lip 4
COSIG Co-Occurring Disorders Conference, Hershey PA, May 15-17, 2006 Deleterious effects appear multifactorial Fetuses are differentially susceptible to the effects of alcohol exposure Type of Teratogenesis Based on Day of Exposure Gestational Day 7 in the mouse lead to facial anomalies, brain anomalies, ocular defects Gestational Day 8 in the mouse lead to cardiac anomalies, skeletal anomalies Alcohol is More Neurotoxic than Cocaine, Heroin, PCP or Marijuana Gestational Day 9 and 10 in the mouse lead to urogenital abnormalities (hydronephrosis, hydroureter) Late 3rd and 4th week post fertilization in the human is the corresponding time that is very vulnerable to producing facial, brain and organ anomalies Cognitive, Behavioral, Emotional and other Problems Can Each Appear Across a Continuum of Severity Cognition Behavior Social Skills Speech and Language Emotion Mild Mild Mild Mild Mild Poor insight and judgment, poor planning, impairment in short term memory and processing speed Aggression, temper outbursts, impulsivity, restlessness, vindictiveness Poor boundaries, difficulty reading facial expressions or body language pragmatic speech, receptive and expressive language anxiety and mood lability Severe Severe Severe Severe Severe Motor Skills Mild Fine, gross motor skills impairment Severe 5
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- Page 509 and 510: MY 9-YR-OLD SON’S HISTORY OF MEDI
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<strong>COSIG</strong> Co-Occurring Disorders Conference, Hershey PA, May 15-17, 2006<br />
Deleterious effects appear multifactorial<br />
Fetuses are differentially susceptible to the<br />
effects of alcohol exposure<br />
Type of Teratogenesis Based on Day<br />
of Exposure<br />
Gestational Day 7 in the<br />
mouse lead to facial<br />
anomalies, brain anomalies,<br />
ocular defects<br />
Gestational Day 8 in the<br />
mouse lead to cardiac<br />
anomalies, skeletal<br />
anomalies<br />
Alcohol is More Neurotoxic than Cocaine,<br />
Heroin, PCP or Marijuana<br />
Gestational Day 9 and 10 in<br />
the mouse lead to urogenital<br />
abnormalities (hydronephrosis,<br />
hydroureter)<br />
Late 3rd and 4th week<br />
post fertilization in the<br />
human is the<br />
corresponding time that is<br />
very vulnerable to<br />
producing facial, brain<br />
and organ anomalies<br />
Cognitive, Behavioral, Emotional and other<br />
Problems Can Each Appear Across a Continuum<br />
of Severity<br />
Cognition<br />
Behavior<br />
Social<br />
Skills<br />
Speech and<br />
Language<br />
Emotion<br />
Mild<br />
Mild<br />
Mild<br />
Mild<br />
Mild<br />
Poor insight and judgment, poor planning,<br />
impairment in short term memory and processing<br />
speed<br />
Aggression, temper outbursts, impulsivity,<br />
restlessness, vindictiveness<br />
Poor boundaries, difficulty reading facial<br />
expressions or body language<br />
pragmatic speech, receptive and<br />
expressive language<br />
anxiety and mood lability<br />
Severe<br />
Severe<br />
Severe<br />
Severe<br />
Severe<br />
Motor Skills<br />
Mild<br />
Fine, gross motor skills impairment<br />
Severe<br />
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