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COSIG CONFERENCE BROCHURE.pdf - Drexel University College ...

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<strong>COSIG</strong> Co-Occurring Disorders Conference, Hershey PA, May 15-17, 2006<br />

Causes of Mood Disorders<br />

• Biological diseases<br />

• Caused by changes in brain chemistry<br />

• No single cause of changes in brain<br />

chemistry<br />

– Episodes occur as a result of genetic,<br />

biological, and psychological influences<br />

combined with life stresses<br />

Common Pathway Hypothesis<br />

(Reinecke & Davison, 2002)<br />

• Interactive model<br />

• Behavioral manifestation of a new<br />

psychobiological state<br />

• Various interlocking processes at the:<br />

– Neurophysiological &<br />

– Biochemical &<br />

– Experiential &<br />

– Behavioral levels<br />

Common Pathway Hypothesis (con’t)<br />

BIOPSYCHOSOCIAL-SPIRITUAL MODEL<br />

(Adapted from Sands, 1991)<br />

BIOLOGICAL<br />

• Affects the limbic-diencephalic-prefrontal<br />

cortex connection<br />

• Builds over many years<br />

• Weaving together of biological, social and<br />

psychological factors<br />

PSYCHOLOGICAL<br />

Genetics<br />

Psychopharmacology<br />

Neurophysiology<br />

Cognition<br />

Emotions<br />

Behaviors<br />

Interactions<br />

Transactions<br />

SPIRITUAL<br />

SOCIAL<br />

Factors Considered in the<br />

Common Pathway Hypothesis<br />

• Genetic vulnerability<br />

• Predisposing temperament<br />

• Character traits<br />

• Age and gender<br />

• Physical illness<br />

Factors Considered in the Common<br />

Pathway Hypothesis (con’t)<br />

• Aging<br />

• Developmental events<br />

• Socio-cultural context<br />

• Major trauma (single event or<br />

ongoing traumatic events)<br />

3

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