COSIG CONFERENCE BROCHURE.pdf - Drexel University College ...

COSIG Co-Occurring Disorders Conference, Hershey PA, May 15-17, 2006
Moody Blues: Co-occurring
Substance Use and Mood
Disorders
Pasquale Russoniello
Epidemiology: Major Depression
(DSM-IV, 1994)
• Depression is estimated to become
the second leading cause of disability
worldwide
• An estimated 17% of adults will have
an episode of major depression in
their lifetime
– 5% of these episodes will last more than
one year
Epidemiology: Major Depression
• 5-10% of adult primary care clients
suffer from major depression
– 8% of primary care clients may have
dysthymia
– Higher rates in institutions
– Increased risk of Alcohol Dependence in
adult first-degree relatives
• 50%-60% with one episode of Major
Depression are likely to have others
National Survey of Major
Depression (NESARC, 2001-2002)
• Increased likelihood of current or lifetime
MDD:
– Middle age – mean age of onset about age 30
– Native American race
– Female gender
– Low income
– Separation, divorced or widowhood
• Nearly one-half wanted to die, one-third
considered suicide and 8.8 % reported one
attempt
NESARC Findings for MDD and
SUDs
• 14% of current MDD persons have a Alcohol use
disorder (AUD) and 4.6 had a drug use disorder
• (higher rates among persons with lifetime MDD –
40% had AUD & 17% had experienced drug
disorder.
• Strong relationship - MDD to substance dependence
and a weak relationship to substance abuse
• Coexisting substance dependence disorder and
MDD predict poor outcome among clinic patients
• Integrated treatment becoming common practice
Epidemiology: Bipolar Disorder
(DSM IV, 1994)
• Lifetime=0.8 to 1.6 percent of the general
population
• Lifetime incidence = 1.6%
• Males and Females equally affected by
Bipolar I Disorder
– Bipolar II is more common in females
• 25-50% attempt suicide
– 11 % die by suicide.
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