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QUALITY OF LIFE - National Cancer Centre Singapore

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PAGE B2<br />

Looking Forward<br />

SALUBRIS<br />

September / October 2011<br />

GYNAECOLOGICAL CANCERS:<br />

TREATMENT AND SCREENING I<br />

COPING WITH<br />

UTERINE (WOMB) CANCER<br />

PAGE B3<br />

Tender Care<br />

SALUBRIS<br />

September / October 2011<br />

Continued from page B1.<br />

The uterus, or womb, is an important female reproductive<br />

organ. The uterus is the pelvic organ that holds the baby during<br />

pregnancy. <strong>Cancer</strong> of the womb (or uterine cancer) usually occurs<br />

after menopause and it is now the 4th most common cancer<br />

among women in <strong>Singapore</strong>. There are about 300 cases diagnosed<br />

annually according to the <strong>Singapore</strong> <strong>Cancer</strong> Registry 2005-2009.<br />

THE COMMON SYMPTOMS<br />

<strong>OF</strong> CERVICAL CANCERS<br />

ARE:<br />

• Bleeding after intercourse<br />

• Bleeding in between menses<br />

• Blood stained or foul smelling<br />

vaginal discharge<br />

• Bleeding after menopause<br />

• Pain is often a late sign of<br />

cervical cancer<br />

Cervical cancer presents as a growth on<br />

the cervix and a biopsy will be taken by the<br />

doctor to confirm the presence of cancerous<br />

cells. Once the cancer is confirmed, the<br />

patient will be referred to a gynaecologic<br />

oncologist for further management,<br />

which entails further investigations to<br />

determine the extent/spread of the cancer.<br />

This often entails imaging studies e.g.<br />

CT scan, MRI and a procedure called<br />

examination under anaesthesia.<br />

For early cancers, the choice of treatment is between surgery and radiotherapy. The choice<br />

will largely be dependent on factors e.g. age, surgical feasibility etc, which the oncologist<br />

will advice accordingly depending on the individual patient. For advanced disease, the<br />

treatment will be radiation concurrent with chemotherapy or chemotherapy.<br />

FIVE-YEAR OUTLOOK<br />

(SURVIVAL) IS<br />

DEPENDENT ON STAGE:<br />

• Stage 1 80-90%<br />

• Stage 2 50-70%<br />

• Stage 3 20-40%<br />

• Stage 4 10-20%<br />

The good news is that cervical cancer can be prevented. Concurrently, one can prevent<br />

cervical cancer by HPV vaccination (primary prevention) and Pap smear (secondary<br />

prevention). There are 2 vaccines available now: Cervarix and Gardasil. The latter covers<br />

subtypes 16 and 18 i.e. the high risk subtypes that account for 70% of cervical cancers,<br />

the latter besides covering subtypes 16 and 18 also covers low risk subtypes 6 and 11 that<br />

causes genital warts. The vaccines are indicated for girls aged 9 to 26. Cervarix is available<br />

at all polyclinics and is medisave deductible. Pap smear screening is recommended for all<br />

sexually active women aged 25 to 65 at least once every three years. The Pap smear test<br />

is a screening test for cervical cancer. It aims to detect precancer changes on the cervix<br />

which can easily be treated so that cancer development can be prevented. It is a simple<br />

and affordable test available at all polyclinics, GPs and Gynaecology Clinics.<br />

As this is a cancer that affects mainly<br />

women after menopause (75% of<br />

cases), the most common presenting<br />

symptom is postmenopausal bleeding (vaginal<br />

bleeding after menopause). However, in<br />

women who are still menstruating, it may<br />

present with heavy irregular periods or<br />

intermenstrual bleeding. There are several<br />

known risk factors for this cancer including:<br />

increasing age, late menopause, obesity, family<br />

history of breast or womb cancer, personal<br />

history of breast cancer, polycystic ovary<br />

syndrome and estrogen only hormone therapy.<br />

Treatment for womb cancer varies depending<br />

on overall health and how advanced the<br />

cancer is. Fortunately, most cancers of the<br />

womb occur at an early stage and surgery<br />

alone is curative. However, some patients<br />

will require further treatment after surgery<br />

if there is evidence of the cancer spreading.<br />

This includes radiotherapy, chemotherapy or<br />

hormonal therapy.<br />

The stage of the cancer will determine<br />

the type of treatment. The cancer is<br />

referred to as early if it remains confined<br />

to the region of the cervix. It is referred to<br />

as advanced if it has spread beyond the<br />

confines of the cervix to the surrounding<br />

organs or distant organs.<br />

By Dr Chia Yin Nin<br />

MBBS(S’pore), MRCOG(UK), FAMS(S’pore), DGO(RANZCOG), GDipHCML(SMU)<br />

Certified Gynaecologic Oncologist<br />

Head & Consultant , Gynaecological <strong>Cancer</strong> Unit, KK Women’s and Children’s Hospital<br />

Adjunct Assistant Professor, Duke’s Medical School, <strong>Singapore</strong><br />

Visiting Consultant, <strong>National</strong> <strong>Cancer</strong> <strong>Centre</strong> <strong>Singapore</strong><br />

Uterine cancer can be particularly difficult<br />

to cope with, physically and emotionally.<br />

Uterine cancer can be particularly difficult<br />

to cope with, physically and emotionally. If<br />

you have cancer, you may often feel tired. It is<br />

important to learn ways to manage symptoms<br />

of cancer and the side effects from cancer<br />

treatment, and to maintain good nutrition and<br />

overall well-being.<br />

Continued on page B4.

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