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Posterior Subtenon Injection of Triamcinalone Acetonide for Cystoid ...

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Visual acuity change by visit<br />

Visual acuity (LogMAR)<br />

1.4<br />

1.2<br />

1<br />

0.8<br />

0.6<br />

0.4<br />

0.2<br />

0<br />

Baseline<br />

1<br />

2<br />

3<br />

4<br />

5<br />

6<br />

7<br />

8<br />

9<br />

10<br />

11<br />

12<br />

13<br />

14<br />

15<br />

16<br />

17<br />

18<br />

19<br />

20<br />

21<br />

22<br />

23<br />

24<br />

Time<br />

PSTI<br />

(Weeks)<br />

Control<br />

Fig. 1. Dynamics <strong>of</strong> mean visual acuity in the PSTI and control eyes throughout the study period<br />

A<br />

B<br />

Fig. 2. Fluorescein angiogram <strong>of</strong> right eye, be<strong>for</strong>e injection (A) the LogMAR acuity 1.0 and 6 months after injection the<br />

LogMAR acuity 0.9. There is a mild reduction <strong>of</strong> dye leakage after 6 months <strong>of</strong> injection (arrow)<br />

IOP changes by visit<br />

16<br />

IOP (mmHg)<br />

15.5<br />

15<br />

14.5<br />

14<br />

13.5<br />

13<br />

Baseline<br />

1<br />

2<br />

3<br />

4<br />

5<br />

6<br />

7<br />

8<br />

9<br />

10<br />

PSTI<br />

11<br />

12<br />

13<br />

Control<br />

14<br />

15<br />

16<br />

17<br />

18<br />

19<br />

20<br />

21<br />

22<br />

23<br />

24<br />

Time (Weeks)<br />

Fig. 3. Mean intraocular pressure in the PSTI and control eyes throughout the study period.<br />

from the baseline measurement was noted. Between<br />

groups, analysis reveals a statistically significant<br />

difference in mean logMAR visual acuity from the<br />

first week <strong>of</strong> observation. At the end <strong>of</strong> the second<br />

month <strong>of</strong> observation the difference reached a<br />

plateau-like maximum. During the next four months<br />

a gradual decrease in visual acuity <strong>of</strong> PSTI group<br />

was noted and this could be related to steroid effect<br />

withdrawal. Accordingly, at week 24 (end <strong>of</strong><br />

observation), the difference in LogMAR acuity<br />

between the two groups diminished, but it was still<br />

significant (p

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