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An assessment of the causes of malnutrition in Ethiopia: A ...

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Box 4.2: Reasons why PLWHA are vulnerable to nutritional <strong>in</strong>security<br />

Increased requirement <strong>of</strong> nutrients because:<br />

• The body's defense system - <strong>the</strong> immune<br />

system - works harder to fight <strong>in</strong>fection and<br />

stress due to free radicals and hence needs<br />

adequate supply <strong>of</strong> free radical scavengers<br />

(micronutrients) to cope with <strong>the</strong> situation<br />

• This <strong>in</strong>creases energy and o<strong>the</strong>r nutrient<br />

requirements. Fur<strong>the</strong>r <strong>in</strong>fection and fever also<br />

<strong>in</strong>crease <strong>the</strong> body's demand for food.<br />

• Once people are <strong>in</strong>fected with HIV <strong>the</strong>y have to<br />

eat more to meet <strong>the</strong>se extra energy and o<strong>the</strong>r<br />

nutrient needs.<br />

• Such needs will <strong>in</strong>crease even fur<strong>the</strong>r as <strong>the</strong><br />

HIV/AIDS symptoms develop and this will lead<br />

to rapid progression to AIDS and early death<br />

(Figure 4.5 shows <strong>the</strong> vicious cycle between<br />

HIV/AIDS and <strong>malnutrition</strong>).<br />

• 10 percent <strong>in</strong>crease <strong>in</strong> energy requirement<br />

dur<strong>in</strong>g asymptomatic <strong>in</strong>fection<br />

• 20-30 percent <strong>in</strong>crease dur<strong>in</strong>g secondary<br />

<strong>in</strong>fections<br />

• 50-100 percent <strong>in</strong>crease for children<br />

(WHO 2003)<br />

Decreased <strong>in</strong>take <strong>of</strong> nutrients because:<br />

• The illness and <strong>the</strong> medic<strong>in</strong>es taken for it may<br />

reduce <strong>the</strong> appetite, modify <strong>the</strong> taste <strong>of</strong> food and<br />

prevent <strong>the</strong> body from absorb<strong>in</strong>g it;<br />

• Symptoms such as a sore mouth, nausea and<br />

vomit<strong>in</strong>g make it difficult to eat;<br />

• Tiredness, isolation and depression reduce <strong>the</strong><br />

appetite and <strong>the</strong> will<strong>in</strong>gness to make an effort to<br />

prepare food and eat regularly;<br />

• There is not enough money to buy food (Food<br />

<strong>in</strong>security/loss <strong>of</strong> livelihoods)<br />

• One <strong>of</strong> <strong>the</strong> consequences <strong>of</strong> HIV and o<strong>the</strong>r<br />

<strong>in</strong>fections is that s<strong>in</strong>ce <strong>the</strong> gut wall is damaged,<br />

food does not pass through properly and is<br />

consequently not absorbed.<br />

• When a person has diarrhea, <strong>the</strong> food passes<br />

through <strong>the</strong> gut so quickly that it is not properly<br />

digested and fewer nutrients are absorbed.<br />

• Metabolic changes<br />

• Cytok<strong>in</strong>e-related changes affect appetite.<br />

• Impaired transport, storage, utilization <strong>of</strong> some<br />

nutrients (e.g. prote<strong>in</strong>).<br />

• Increased utilization <strong>of</strong> antioxidant vitam<strong>in</strong>s and<br />

enzymes, result<strong>in</strong>g <strong>in</strong> oxidative stress.<br />

As shown <strong>in</strong> Box 4.2, when <strong>in</strong>fected with <strong>the</strong> HIV virus, <strong>the</strong> body will be challenged<br />

with two problems: <strong>in</strong>creased requirement and decreased <strong>in</strong>take <strong>of</strong> nutrients.<br />

Therefore, people liv<strong>in</strong>g with HIV/AIDS (PLWHA) are very vulnerable to nutrition<br />

<strong>in</strong>security due to both biological and social reasons. Nutritional care <strong>of</strong> PLWHA helps to<br />

Figure 4.5: The vicious cycle <strong>of</strong> HIV/AIDS and <strong>malnutrition</strong><br />

• Increased HIV<br />

replication<br />

• Hastened disease<br />

progression<br />

• Increased morbidity<br />

• Insufficient dietary<br />

<strong>in</strong>take; malabsorption<br />

• Diarrhea<br />

• Altered metabolism &<br />

nutrient storage<br />

• Increased<br />

oxidative stress<br />

• Immune<br />

suppression<br />

• Nutritional<br />

deficiencies<br />

Source: Adapted from Semba & Tang 1999<br />

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