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Material Infomiation on <strong>Mentha</strong> <strong>arvensis</strong> <strong>oil</strong><br />
RIFM - FEMA Database<br />
-- .<br />
<strong>Mentha</strong> <strong>arvensis</strong> <strong>oil</strong> Monograph<br />
<strong>Mentha</strong> <strong>arvensis</strong> <strong>oil</strong><br />
_ --<br />
Synonyms ~<br />
~Cornmmt <strong>oil</strong> - - ~ ~2IFM I<br />
L _-- _ - -<br />
[Commint <strong>oil</strong> (dementfiolized)l [FMA I<br />
Japanese --<br />
-<br />
L mmtol_ ----<br />
I<strong>Mentha</strong> arvems (Zainiaceae) [Botanicall<br />
llvfentha <strong>arvensis</strong>, ext. I LINECS ~<br />
Clvlentha arvensi-s<strong>oil</strong>_ ~ [Principal I<br />
CAS Number Monograph EINECS Registration<br />
68917-18-0 W509 W,' 290-058-5 EINECS DSL TSCA<br />
RIFM Monograph : 509 (Published 1975 : FCT,v13,p771, Special Issue II (Binder, p258))<br />
Generic Class Essential Oils and Resins<br />
Description A clear yellow to light amber mobile liquid with a peppermint-like odor .<br />
Component Substances The main constituent of cornmint <strong>oil</strong> is 1-menthol (Guenther,1949) .<br />
Physical Data<br />
Ester Va ue a er cety ation<br />
5%- 20%<br />
(X .<br />
- --rIash Pomt 150°F~M-<br />
- -<br />
Ketone Content (X .X.C .2) 30% - 50%<br />
FMA<br />
MA<br />
FMA<br />
10 .0 g .jAs menthyl acetate (Cl<br />
2 g lCalcu ated as menthone<br />
(C<br />
OH-Value-(Tota A coho s X.B--.T.e) 4 °Io---6ObT - FIvI 2 g. s mentho ( H 00)<br />
0-pticaf R-otation-(I:C) - 5 to - - - FMK- -<br />
Rctrve In ex a 20°C~T.~ 1.45$ 1 .~65 FIv1A- ~<br />
-- aponification-Va-lue 5°l0 -/o FMK- 5 g(As menthyl acetate<br />
Somb7hty m ATcoTioT(XXIV) 1 m~3Tiy vo . FM~ _~jUse 7b~Ethano ~<br />
- peci ~c~vity ~b°C (I. ~$91~.911 FIv1A<br />
- -gp-eci ftc raGity2-5°CTI-. 0.88 8--- .90 FIvI-K-<br />
- - - -<br />
UV Absorbance --<br />
peak at 257 nm<br />
Vapor Pressure (calculated) d0C m Hg<br />
RlF<br />
1974<br />
FMA<br />
74-63<br />
http ://rifm .org/d . . .IMaterial. cfm?CASNumber--68917-18-0&CFID=101164&CFTOKEN=319 11I%11799>b<br />
http://legacy.library.ucsf.edu/tid/ugy20d00/pdf<br />
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Material Information on <strong>Mentha</strong> <strong>arvensis</strong> <strong>oil</strong> Page 2 of 2<br />
Preparation By steam distillation of the budding overground parts of the plant of M. <strong>arvensis</strong><br />
var . piperascens Holmes, followed by the partial dementholization by <strong>arvensis</strong><br />
crystallization . (Guenther, 1949)<br />
_ _ --: --<br />
~ Natural<br />
-- ..<br />
<strong>Mentha</strong> <strong>arvensis</strong> <strong>oil</strong> is a botanical derivative<br />
Occurrence<br />
.<br />
-- - -- -<br />
Use Levelsl `In<br />
-<br />
pubhc<br />
-<br />
use since<br />
-----<br />
the 1950s .<br />
-- -=----,- --_ -_ _,<br />
- - -- -~<br />
Status<br />
<strong>Mentha</strong> <strong>arvensis</strong> <strong>oil</strong> was included by the Council of Europe in the list of substances granted<br />
Approval (COE No . 492) .<br />
Other Actions<br />
European Inventory of Existing Commercial Chemical Registered as 90063-97-1 ( 290-058-<br />
Substance 5)<br />
RIFM - FEMA Database<br />
Indicative Non-Exhaustive List of fragrance ingredients<br />
FFIDS Volume NEW<br />
6/88 . clarify confusion in mint <strong>oil</strong>s .<br />
Hazard Statements<br />
22-Sep-93 R22 Harmful if swallowed .<br />
Human ea a a<br />
Environmental Data<br />
Other References to <strong>Mentha</strong> <strong>arvensis</strong> <strong>oil</strong><br />
http ://ri fin .org/d . . ./Material.cfm?CASNumber-68917-18-0&CFID=101164&CFTOKEN=319 11 /11 /99<br />
http://legacy.library.ucsf.edu/tid/ugy20d00/pdf
Material Experiments for <strong>Mentha</strong> <strong>arvensis</strong> <strong>oil</strong><br />
f<br />
Page 1 of I<br />
RIFM - FEMA Database<br />
1 Acute toxicity LD50<br />
2 Acute toxicity LD50<br />
3 Acute toxicity<br />
4 Acute toxicity<br />
5 Acute toxicity<br />
6 Acute toxicity<br />
7 Irritation<br />
8 Irritation<br />
9 Irritation<br />
I OPatch test<br />
11 Maximization<br />
12Phototoxicity<br />
13Phototoxicity<br />
14Phototoxicity<br />
15Phototoxicity<br />
16Phannacology<br />
17Interaction<br />
18Mutagenicity<br />
19Mutagenicity<br />
2OMutagenicity<br />
21Reproductive<br />
22Reproductive<br />
23Reproductive<br />
24Reproductive<br />
25Reproductive<br />
26Cytotoxicity<br />
27Antimicrobial<br />
28Antimicrobial<br />
29Antimicrobial<br />
30Antimicrobial<br />
31 Antimicrobial<br />
32Antimicrobial<br />
33Unclassified<br />
34Unclassified<br />
35Unolassified<br />
36Unclassified<br />
37Unclassified<br />
38Unclassified<br />
39Acute toxicity LC50<br />
40Unclassified<br />
41Unclassified<br />
RIFM - FEMA Database<br />
To <strong>Mentha</strong> <strong>arvensis</strong> <strong>oil</strong><br />
Material Experiments for <strong>Mentha</strong> <strong>arvensis</strong> <strong>oil</strong><br />
oral<br />
skin<br />
in vitro<br />
in vitro<br />
in vitro<br />
in vitro<br />
skin<br />
skin<br />
skin<br />
skin<br />
skin<br />
skin<br />
skin<br />
skin<br />
skin<br />
in vitro<br />
skin<br />
in vitro<br />
in vitro<br />
in vitro<br />
subcutaneous<br />
subcutaneous<br />
subcutaneous<br />
oral<br />
intramuscular<br />
in vitro<br />
in vitro<br />
in vitro<br />
in vitro<br />
in vitro<br />
in vitro<br />
in vitro<br />
in vitro<br />
in vitro<br />
in vitro<br />
in vitro<br />
Human Health Data<br />
rat<br />
rabbit<br />
Escherichia coli<br />
Bacillus subtilis<br />
bacteria<br />
fungi<br />
mouse<br />
pig<br />
man<br />
man<br />
man<br />
mouse<br />
mouse<br />
pig<br />
pig<br />
domestic animals<br />
in vitro fungi<br />
in vitro fungi<br />
Environmental Data<br />
in vitro insect<br />
unclassified insect<br />
unclassified insect<br />
Wohl,1974<br />
Woh1,1974<br />
Sanyal,1969<br />
Sanyal,1969<br />
Sanyal,1969<br />
Sanyal,1969<br />
Urbach,1974<br />
Urbach,1974<br />
Epstein,1974<br />
Kobayashi, 1996b<br />
Epstein,1974<br />
Urbach,1974<br />
Forbes,1977<br />
Forbes,1977<br />
Urbach,1974<br />
Miyazawa,1998<br />
mouse Yasukawa, 1993<br />
Bacillus subtilis Morimoto,1982<br />
S almonella typhimurium Morimoto,1982<br />
Salmonella typhimurium Morimoto,1982<br />
rat Kanjanapothi,1981<br />
rat Kanjanapothi,1981<br />
rat Kanj anapothi,1981<br />
mouse Sharma,1997b<br />
mouse Sharma,1996<br />
not applicable Siljanowska,1969<br />
bacteria Suri,1992<br />
bacteria Rao,1978<br />
bacteria Singh, 1992<br />
fungi Singh,1992<br />
not applicable Morris,1979<br />
bacteria Begum,1993<br />
fungi Arora,1977<br />
fungi Arora,1977<br />
guinea pig Kishore,1993<br />
fungi Kishore,1993<br />
Singh,1989<br />
Kishore,l993<br />
Kumar, 1987<br />
Katiyar,1984<br />
Singh,1995b<br />
http . . ./m ateri alexperiments . cfm?CASNumber=68917-18-0&CFID=101164&CFTOKEN=319 11 / 11/99<br />
http://legacy.library.ucsf.edu/tid/ugy20d00/pdf