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Invasive breast carcinoma - IARC

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TNM classification of <strong>carcinoma</strong>s of the vulva<br />

TNM Classification 1,2<br />

T – Primary Tumour<br />

TX<br />

T0<br />

Tis<br />

T1<br />

T1a<br />

T1b<br />

T2<br />

T3<br />

T4<br />

Primary tumour cannot be assessed<br />

No evidence of primary tumour<br />

Carcinoma in situ (preinvasive <strong>carcinoma</strong>)<br />

Tumour confined to vulva or vulva and perineum, 2 cm or less in<br />

greatest dimension<br />

Tumour confined to vulva or vulva and perineum, 2 cm or less in<br />

greatest dimension and with stromal invasion no greater than 1 mm<br />

Tumour confined to vulva or vulva and perineum, 2 cm or less in<br />

greatest dimension and with stromal invasion greater than 1 mm<br />

Tumour confined to vulva or vulva and perineum, more than 2 cm in<br />

greatest dimension<br />

Tumour invades any of the following: lower urethra, vagina, anus<br />

Tumour invades any of the following: bladder mucosa, rectal<br />

mucosa, upper urethra; or is fixed to pubic bone<br />

Note: The depth of invasion is defined as the measurement of the tumour from the<br />

epithelial-stromal junction of the adjacent most superficial dermal papilla to the<br />

deepest point of invasion.<br />

N – Regional Lymph Node s 3<br />

NX Regional lymph nodes cannot be assessed<br />

N0 No regional lymph node metastasis<br />

N1 Unilateral regional lymph node metastasis<br />

N2 Bilateral regional lymph node metastasis<br />

M – Distant Metastasis<br />

MX Distant metastasis cannot be assessed<br />

M0 No distant metastasis<br />

M1 Distant metastasis (including pelvic lymph node metastasis)<br />

Stage Grouping (TNM and FIGO)<br />

Stage 0 Tis N0 M0<br />

Stage I T1 N0 M0<br />

Stage IA T1a N0 M0<br />

Stage IB T1b N0 M0<br />

Stage II T2 N0 M0<br />

Stage III T1, T2 N1 M0<br />

T3 N0, N1 M0<br />

Stage IVA T1, T2, T3 N2 M0<br />

T4 Any N M0<br />

Stage IVB Any T Any N M1<br />

_ _ _ _ _ _ _ _ _ _<br />

1<br />

{51,2976}.<br />

2<br />

A help desk for specific questions about the TNM classification is available at http://tnm.uicc.org.<br />

3<br />

The regional lymph nodes are the femoral and inguinal nodes.<br />

315

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