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BIBLIOGRAPHIC INPUT SHEET TEMPORARY Patterns of mortality ...

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Chapter V. Infant Mortality<br />

75<br />

Preeclampsia <strong>of</strong> pregnancy<br />

Premature separation <strong>of</strong> placenta<br />

Immaturity<br />

Respiratory distress syndrome<br />

Hemorrhagic disease <strong>of</strong> the newborn<br />

(terminal)<br />

At the time <strong>of</strong> death neither the maternal<br />

nor the placental conditions were acting<br />

upon this child. The immaturity or prematurity<br />

was a consequence <strong>of</strong> the preeclampsia<br />

and its complication (premature<br />

separation <strong>of</strong> placenta) and at the same<br />

time was an important factor in the development<br />

<strong>of</strong> the respiratory distress and<br />

hemorrhagic condition. The only cause<br />

mentioned in the medical certificate <strong>of</strong><br />

cause <strong>of</strong> death was prematurity, yet all the<br />

necessary information related to the underlying<br />

cause and its consequences was available<br />

in the hospital record. The sequence<br />

element is very important to an understanding<br />

<strong>of</strong> the cause-effect relationship within<br />

the multiple-cause constellation in this age<br />

period, and it is essential that the maternal,<br />

fetal, obstetric, and postnatal factors be<br />

taken into account in order to provide adequate<br />

medical care.<br />

Undoubtedly, <strong>of</strong>ficial <strong>mortality</strong> statistics<br />

would improve greatly if all the diagnoses<br />

stated in the death certificate were used in<br />

the analyses <strong>of</strong> causes <strong>of</strong> death. A consultant<br />

group convened by the World<br />

Health Organization in October 1969 for-<br />

connected with an obstetric or prenatal condition.<br />

The diabetic mother, for example,<br />

could after difficult labor give birth to an<br />

abnormally large baby susceptible to hypoglycemia<br />

and respiratory distress.<br />

The following example taken from the<br />

Investigation illustrates the complexity <strong>of</strong><br />

multiple causes <strong>of</strong> death in this age group.<br />

A child who died at 3 days <strong>of</strong> age was a<br />

product <strong>of</strong> a seven-month pregnancy and<br />

born to a preeclamptic mother who had a<br />

partial separation <strong>of</strong> placenta prior to<br />

delivery. At birth, the infant's weight was<br />

1,030 grams and its condition fair. The<br />

clinical course was characterized by pro­<br />

gresssive respiratory distress and death<br />

occurred on the third day after an episode<br />

<strong>of</strong> bleeding from the respiratory and diges­<br />

tive systems.<br />

The multiple causes assigned were:<br />

762.1 Underlying cause<br />

770.1<br />

777<br />

776.2 Consequences<br />

778.2<br />

mulated similar recommendations in regard<br />

to analyses and basic tabulations <strong>of</strong> multiple<br />

causes <strong>of</strong> <strong>mortality</strong> using death certificates<br />

as source <strong>of</strong> data (WHO, 1969).<br />

An even greater benefit would be obtained<br />

if selected centers, at least, could<br />

routinely collect information complementary<br />

to the medical certificate <strong>of</strong> death,<br />

using data from clinical histories and<br />

autopsies (Puffer, 1970). All actions aimed<br />

at improving the quality <strong>of</strong> clinical histories,<br />

autopsies, and death certificates will<br />

contribute toward improvement <strong>of</strong> the information<br />

needed for a successful study <strong>of</strong><br />

multiple causes <strong>of</strong> <strong>mortality</strong>.<br />

Only through the multiple-cause approach<br />

is it possible to measure the real<br />

magnitude <strong>of</strong> serious health problems that<br />

have remained occult because studies were<br />

based only on single causes. The method<br />

used in this Investigation involves a<br />

sequential or chronological interrelationship,<br />

which is at times difficult to establish.<br />

Nevertheless, the effort made is recommended<br />

for other community-centered in­<br />

vestigations since it provides an excellent<br />

epidemiologic experience with aspects that

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