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BIBLIOGRAPHIC INPUT SHEET TEMPORARY Patterns of mortality ...

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Chapter V<br />

Infant Mortality<br />

The dynamic and complex process <strong>of</strong><br />

growth and development is the outstanding<br />

characteristic <strong>of</strong> the early life <strong>of</strong> the infant<br />

(as it is <strong>of</strong> the rest <strong>of</strong> childhood). This<br />

process-a continuous one under normal<br />

conditions-begins with a state <strong>of</strong> complete<br />

dependency on the mother during intrauterine<br />

life and progresses in a complex and<br />

sometimes unfavorable enviromnent (luring<br />

and after birth. Countless factors can interfere<br />

with the normal evolution <strong>of</strong> this<br />

process and hence with the health <strong>of</strong> the<br />

child.<br />

The interrelationships <strong>of</strong> factors affecting<br />

the mother, the fetus, delivery, and postnatal<br />

development constitute an extremely<br />

important field for analysis in the study <strong>of</strong><br />

multiple causes and conditions responsible<br />

for morbidity and <strong>mortality</strong>. For an understanding<br />

<strong>of</strong> these interrelationships and associations,<br />

it is necessary to take into<br />

account also the chain <strong>of</strong> events leading to<br />

death.<br />

Closely related to these considerations is<br />

the evidence that diseases and their effects<br />

are not static. The impact that a morbid<br />

condition may produce on health depends to<br />

a great extent on the state <strong>of</strong> the host-that<br />

is, stage <strong>of</strong> development, previous illnesses,<br />

and existence <strong>of</strong> concomitant pathological<br />

processes. In an age group in which growth<br />

and development are biological necessities,<br />

recurrent episodes <strong>of</strong> one or more diseases<br />

have additive or compounded effects;<br />

repetition <strong>of</strong> an apparently mild process can<br />

lead to a critical state <strong>of</strong> health and even to<br />

death. Typical examples are the very coinmon<br />

problems <strong>of</strong> diarrheal diseases and<br />

respiratory infections which, through 1'epeated<br />

episodes, build susceptibility to a<br />

point where one episode that would be<br />

trivial for a healthy child becomes fatal.<br />

Finally, it is known that morbid conditions<br />

may have reciprocal and even synergistic<br />

effects, and therefore effective measures directed<br />

toward reducing <strong>mortality</strong>, besides<br />

saving lives, undoubtedly have vital roles<br />

in improving the future <strong>of</strong> survivors.<br />

In this chapter, the multiple-cause approach<br />

is described first, and data are then<br />

presented on <strong>mortality</strong> for the entire infant<br />

period by causes, underlying as well as<br />

associated, and on <strong>mortality</strong> for the neonatal<br />

and postneonatal periods. Neonatal<br />

<strong>mortality</strong> is analyzed in further depth in<br />

Chapter VI.<br />

MULTIPLE CAUSES OF DEATH<br />

In the Investigation the term "cause" is is involved either directly or indirectly in<br />

used to designate whatever disease, syn- the process <strong>of</strong> death.<br />

drome, morbid state, or pathologic condition Taking into account the serious diflicul­<br />

73

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