BIBLIOGRAPHIC INPUT SHEET TEMPORARY Patterns of mortality ...

BIBLIOGRAPHIC INPUT SHEET TEMPORARY Patterns of mortality ... BIBLIOGRAPHIC INPUT SHEET TEMPORARY Patterns of mortality ...

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Chapter XVIII Highlights and Recommendations The Inter-American Investigation of Mortality in Childhood, in which 35,095 deaths of children under 5 years of age were studied in 15 different projects, has uncovered and measured health problems for which solutions must be sought. This heinispheric research project has demonstrated the great value of geographic studies of mortality with comparisons of the findings in widely separated areas. The patterns in each of the areas studied appear to be distinct; no two projects had the same type or size of problems. Therefore, the findings in each area make a unique contribution to knowledge of conditions in the locality, state, province, and country in which the project was situated, while at the same time adding to the understanding of health problems of the Hemisphere and of the world. Highlights of the Investigation are given in this chapter, along with recommendations concerning action that could be taken at the local, national, and international levels for the improvement of health in childhood, which in essence means improvement of the health of families, communities, and nations. HIGHLIGHTS Fifteen concise statements of the findings of the Investigation are given as highlights, Although nutritional deficiency is considered the outstanding problem and is stated first, the order of the others does not necessarily reflect their relative importance. Many of the problems are closely interrelated, and their analysis makes clear the need for a comprehen sive approach in health planning in order to attain the overall objective of maternal and child health programs, that is, optimum growth and development of children as an indispensable requirement for the well-being of societies. 345 First. Nutritional deficiency was the most serious health problem uncovered in the Investigation, as measured by its involvement in mortality. This condition is coupled with low weight at birth, and the two conditions combined are endangering the survival and hampering the growth and development of infants and young children and probably of future mothers. Through the study of mortality by multiple causes, 57.0 per cent of the children who died under 5 years of age were found to have had immaturity or nutritional deficiency as either the underlying or an associated cause of

346 Patternsof Mortalityin Childhood death. In several areas two-thirds of the deceased children had such evidence of increased susceptibility to disease. Immaturity indicates a deficit in growth and development of the infant at birth, and low birth weights are believed to be attributable at least in part to the poor nutritional state of the mothers. Breaking this vicious cycle is mandatory. Mothers must be provided with sufficient food of good quality so that they will be able to produce healthy children. Immaturity and nutritional deficiency were found to be even more serious in rural areas thnn in the neighboring cities, the magnitude of these problems in the rural sector of Latin America having been uncovered for the first time in the Investigation. The impact of nutritional deficiency and low birth weight at a stage when the infant normally undergoes rapid growth and developmcnt should be considered not only in terms of mortality but also and principally in terms of the effects on the future health of the survivors, Second. For the first time mortality from nutritional deficiency has been analyzed by age at death and by type of deficiency, and a geographic description has been provided for urban and rural populations in 13 projects in widely separated areas of Latin America. The peak of mortality from nutritional deficiency was in infancy, as early as the third and fourth months of life, but the patterns differed markedly in the 13 projects. In six projects mortality was excessive early in life, in the first few months; in six others high rates extended into the second year; and in the rural areas of the El Salvador project mortality from this cause continued during the first five years of life. Mortality from protein malnutrition increased to its peak in children 12-17 months of age, while nutritional marasmus caused high rates in infants from 2-6 months old. Third. Only through the study of multiple causes was it possible to measure the magnitude of health problems in infancy and childhood. Analyses of associated as well as underlying causes of death were necessary in order to uncover important interrelationships such as the synergistic action of infectious diseases and nutritional deficiency, and the effects of complications of pregnancy and childbirth on products of gestation as measured by weight and condition of the newborn. To implement the recommendation made after the first Inter-American Investigation of Mortality in adults (1962-1964), this Investigation has sought to study the epidemiology of diseases, not by isolated entities but by analyzing combinations of pathological states. Modern data processing methods, including tabulation by computer, have proved valuable in carrying out these analyses of multiple causes. Use of such tabulations and analyses should be extended widely for the study of vital statistics in cities and other selected areas where satisfactory data can be obtained in developing countries, as well as in highly developed countries of the world. Fourth. Official mortality statistics fail to reveal the real magnitude of health problems. in the Investigation registration of neonatal deaths was found to be so incomplete that it is certain that mortality in this period of life has not been sufficiently known. For the 15 projects combined, 13.2 per cent of the neonatal deaths had not been registered; in one project half had not been registered, and in two others more than one-fourth. The outcome of each pregnancy

346 <strong>Patterns</strong><strong>of</strong> Mortalityin Childhood<br />

death. In several areas two-thirds <strong>of</strong> the<br />

deceased children had such evidence <strong>of</strong> increased<br />

susceptibility to disease.<br />

Immaturity indicates a deficit in growth<br />

and development <strong>of</strong> the infant at birth, and<br />

low birth weights are believed to be attributable<br />

at least in part to the poor nutritional<br />

state <strong>of</strong> the mothers. Breaking this<br />

vicious cycle is mandatory. Mothers must<br />

be provided with sufficient food <strong>of</strong> good<br />

quality so that they will be able to produce<br />

healthy children.<br />

Immaturity and nutritional deficiency<br />

were found to be even more serious in rural<br />

areas thnn in the neighboring cities, the<br />

magnitude <strong>of</strong> these problems in the rural<br />

sector <strong>of</strong> Latin America having been uncovered<br />

for the first time in the Investigation.<br />

The impact <strong>of</strong> nutritional deficiency and<br />

low birth weight at a stage when the infant<br />

normally undergoes rapid growth and developmcnt<br />

should be considered not only<br />

in terms <strong>of</strong> <strong>mortality</strong> but also and principally<br />

in terms <strong>of</strong> the effects on the future<br />

health <strong>of</strong> the survivors,<br />

Second. For the first time <strong>mortality</strong> from<br />

nutritional deficiency has been analyzed by<br />

age at death and by type <strong>of</strong> deficiency, and<br />

a geographic description has been provided<br />

for urban and rural populations in 13 projects<br />

in widely separated areas <strong>of</strong> Latin<br />

America.<br />

The peak <strong>of</strong> <strong>mortality</strong> from nutritional<br />

deficiency was in infancy, as early as the<br />

third and fourth months <strong>of</strong> life, but the<br />

patterns differed markedly in the 13 projects.<br />

In six projects <strong>mortality</strong> was excessive<br />

early in life, in the first few months; in six<br />

others high rates extended into the second<br />

year; and in the rural areas <strong>of</strong> the El Salvador<br />

project <strong>mortality</strong> from this cause<br />

continued during the first five years <strong>of</strong> life.<br />

Mortality from protein malnutrition increased<br />

to its peak in children 12-17 months<br />

<strong>of</strong> age, while nutritional marasmus caused<br />

high rates in infants from 2-6 months old.<br />

Third. Only through the study <strong>of</strong> multiple<br />

causes was it possible to measure the<br />

magnitude <strong>of</strong> health problems in infancy<br />

and childhood. Analyses <strong>of</strong> associated as<br />

well as underlying causes <strong>of</strong> death were<br />

necessary in order to uncover important<br />

interrelationships such as the synergistic<br />

action <strong>of</strong> infectious diseases and nutritional<br />

deficiency, and the effects <strong>of</strong> complications<br />

<strong>of</strong> pregnancy and childbirth on products <strong>of</strong><br />

gestation as measured by weight and condition<br />

<strong>of</strong> the newborn.<br />

To implement the recommendation made<br />

after the first Inter-American Investigation<br />

<strong>of</strong> Mortality in adults (1962-1964), this<br />

Investigation has sought to study the epidemiology<br />

<strong>of</strong> diseases, not by isolated entities<br />

but by analyzing combinations <strong>of</strong><br />

pathological states. Modern data processing<br />

methods, including tabulation by computer,<br />

have proved valuable in carrying out these<br />

analyses <strong>of</strong> multiple causes. Use <strong>of</strong> such<br />

tabulations and analyses should be extended<br />

widely for the study <strong>of</strong> vital statistics in<br />

cities and other selected areas where satisfactory<br />

data can be obtained in developing<br />

countries, as well as in highly developed<br />

countries <strong>of</strong> the world.<br />

Fourth. Official <strong>mortality</strong> statistics fail<br />

to reveal the real magnitude <strong>of</strong> health<br />

problems. in the Investigation registration<br />

<strong>of</strong> neonatal deaths was found to be so incomplete<br />

that it is certain that <strong>mortality</strong><br />

in this period <strong>of</strong> life has not been sufficiently<br />

known. For the 15 projects combined, 13.2<br />

per cent <strong>of</strong> the neonatal deaths had not<br />

been registered; in one project half had not<br />

been registered, and in two others more than<br />

one-fourth. The outcome <strong>of</strong> each pregnancy

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