BIBLIOGRAPHIC INPUT SHEET TEMPORARY Patterns of mortality ...

220 Patternsof Mortalityin Childhood
Official data, 1967
(1V1O)
All leu.
forms kedia
Canada 0.5 4.3
Chilo 0.0 3.3
Colombia 5.0 2.6
El Salvador 1.0 0.3
Mexico 3.1 .5
United States 7.7 3.6
Investigation
All Leaforms
kemia
Sherbrooke 12.1 7.7
Chile project
Call
10.6
6.9
5.8
3.0
Cartagenn 8.1 2.3
M1lelln 8.6 2.1
El Salvador
project 2.4 0.8
Monterrey 5.5 2.8
California project 8.3 4.0
Although the numbers of deaths in the SAm JUAN PIOVINCE
Investigation and for the countries (except lllio PAN
the United States) were stnall
smal
and
andCAITA611
variations
can I)e expected from year to year, the 'OLIVIA PROJECT
TTERLL
CHACO PROVLICE
rates per 100,000 population were consistently
li.,her in the Investigation for all tIllii0
HL SALVATOo POJTECT OTHER MALIGNANT NEOPLASMS
,l_1_
foris of Ilh-lignlnt neol)lasins anti for leukenia
(except in two projects in Colombia
Thus, tIle Investigation has revealed the size
of this serious prol)]lei iore completely
than has been known previously.
Since all but 17 of the deaths fron these
mal1ignlatnt diseases occurled in the age
group 1-4 years, the death rates are shown
in Figure 110 only for that age period. The
rates for leukenia ranged fron a high of
8.1 to a low of 1.0 per 100,000 population,
the highest figures being in the projects in
Sherbrooke and Chile. The rates for the
other maliglant niCoplasms were around 4
per 100,010 population (fron 2.9 to 5.4) in
eight I'oje'ts. Four projects had higher
rates: Ribeir'o Prto (10.8), Medellin (8.0),
Cartagena (7.3), and Siio Paulo (6.9);
Recife and El Salvador had very low rates
(with only one and two deaths) and no
deaths occurred in San Juan Province.
The specific sites of the malignant neo-
1)laslns are given in Table 128 for the 15
)rojects.
Evidence was available to support the diagnoses
of leukemia and other neoplasms
for 159 of the 163 deaths, as is shown in
Fla. 110. Mortality from Leukemia and, Other
Malinant Neoplasms in Children 14 Years of
Age in 15 Projects.
|fElnl00gl -
CHIEF PROJECT
CtLfORLIA PROJECT
KIG510141. AtREW
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Cal
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1iOPAuLO
IRnOOTEl
CHILE 111011(l
CALIIORIA PROJECT
1ES11.S. ANtREW
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CH0A1OPROOtC
RECIfE
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SAN Ful tROVICE
DOEATHS PEI 100.000 POPULATION
0 2 d 6 a to of
-
LEUKEMIA
Table 129. The diagnoses were very well
documented. Hematologic studies with or
without other evidence substantiated 63 of
the deaths due to leukemia, and biopsies
were performed for 63 of the other malignant
neoplasms. Autopsies were performed
in 57 of the deaths. Unfortunately, three
hospital records were lost and in four instances
surgery was performed without
mention of histologic examination. In addition
to these well-documented deaths it is
likely that a few others occurred in which
no diagnostic tests were recorded or performed,
and therefore these were not included
in this series for lack of evidence of
malignancies.