BIBLIOGRAPHIC INPUT SHEET TEMPORARY Patterns of mortality ...
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BIBLIOGRAPHIC INPUT SHEET TEMPORARY Patterns of mortality ...

BIBLIOGRAPHIC INPUT SHEET TEMPORARY Patterns of mortality ... BIBLIOGRAPHIC INPUT SHEET TEMPORARY Patterns of mortality ...

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Chapter X. Congenital Anomalies 215 CONGENITAL ANOMALIES OF OTHER SYSTEMS Anomalies of the respiratory system were found in 71 deceased infants in 15 l)rojects combined (Table 103). In 14 of these (lentils the anomalies were unrelated to the process of death. In tile California project, in 23 out of tie 26 infant deaths due to these conditions they acted as underlying or assoeiated causes, Illost of the deatis (20) being due to Ipulmonary hypoplasia Icategory 748.6). All eight anomalies of the resp)iratory system in the Sherbrooke Iprojeet acted as associated causes, and four of them were contrii)utorv to allsence of diaphragnl (756.8k as unlierlying ealus,. Another was associated with aneneeplhalus as underlying cause and also with absence of diaphragm as associated cause. In one death plilllonary hypoi)lasia was associated witil cystic fibrosis T273.0 1. Another of these anolmalies was associated witil renal agenesis an(l tile last of the eight was associated with (oaretation of aorta 1747.11 as underlying cause. Clubfoot (754) was found in 178 deceased infants and was unrelated to the process of death in 175. In the remaining three infants, a complication of trealtment triggered the chain of events leading to death. Tile highest rates for this anomnaly were found in San .huan Province and in tile Chilean project, where there were 72.8 and 62.0 leceased infants with clubfoot per 100,000 live birth,, respectively. Among the 370 infant (leatils in which ol0r anomalies of the museuloskeletal system such (755, conditions 756) were involved found, as in underlying only 109 were or associated causes. In 52 of these 109 (lentils they were underlying causes; 50 belonged to category 756 and the other two were assigned to (atgoy 755. The other 57 deesed infnts had 44 omlieos belonging to category 756 as assoeinted causes and only 13 assigned to category 755, also as associated ealses. Therefore. it seems oxidIlt that conditions in entegory 7,56 are more sorioue from tle standpoint of mortality than those in categories 754 and 755. MORTALITY BY AGE OF MOTHER Tile influence of maternal age on anomalies in the products of gestation is usually an important factor. In this presentation tile death rates by maternal age have been shown for Down's disease and for anolialies of tile nervous and tile circulatory systems. Augmented rates were noted with increased Imaternal age ill )own's disease, whicih ilrobably raised the rates for anomalies of the circulatory system owing to tile frequent association of these two conditions (10.3 per cent of the deceased infants with cirdulatory anomalies had Down's disease as well). In Table 125 the distribution of deceased infants with congenital anonlalies is given by age of mother at tile infant's birth. Of tile total, 32.8 per cent were born to mothers aged 30 years and over (excluding those with age unknown). This nereentae is

216 Patternsof Mortality in Childhood by Age of Mother in 15 Projects. TABLE 125. Deaths of Infants with Congenital Anomalies Under 20-24 25-29 30-34 35 years Unknown Total 20 years years years years a r Total ........................... 2,873 373 788 030 410 465 207 ARGENTINA Chaco Province ............... .. 74 18 15 18 San Juan Province .............. 176 23 52 38 BOLIVIA project................. 92 5 20 18 IRAZIL Recife ......................... 206 35 44 52 Ribeirao Prto.................. 101 5 SAo Paulo ...................... 458 39 CANADA 11 11 1 28 29 0 13 21 15 17 35 23 30 20 11 17 12 150 124 65 53 27 10 21 2 Shcrbrooke ..................... 124 7 47 31 CHILE project ................... 307 37 83 09 50 60 8 COLOMBIA 107 17 28 10 16 12 15 Call ........................... 8 13 40 Cartagena ..................... 110 10 21 18 28 10 17 32 10 Medellln ....................... 126 20 EL SAIVAI)OR project .......... 210 38 03 35 36 42 2 JAMAICA Kingston-St. Andrew............ 201 38 55 51 23 26 8 MEXICO Monterrey ..................... 353 30 70 02 68 77 34 UNITED STATES California project ............... 222 45 70 50 31 10 4 similar to the percentage of live births projects were the rates for mothers aged 35 among mothers 30 years and over in tile years and over higher than for mothers Chaco Province and Monterrey projects but under 20 years (Sherbrooke, Chile, El Salvahigher than that in the other five projects dor, and Monterrey). In Figure 108, the with maternal ages for live b6i.ths known rates with Down's disease excluded are (Table 148 of Chapter XII). Sllown by t broken linp. Some increase with The death rates in the seven projects for age remained in all four projects. which the distribution of live births by Although differences were noted, similarimothers' age were available are given in ties also were observed. For example, the Table 126 and in Figure 108. In only foul' death rates for the infants of young mothers TABLE 126. Mortality' of Infants with Congenitnl Anomalies by Age of Mother in Seven Projects. ARGEN- EL SAL- UNITED TINA BRAZIL CANADA CILE VADOIt MEXICO California STATES Age of mother Chaco Slo Paulo Sherbrooke project project AMonterrey Province project Total ..................... 420.5 787.5 730.7 704.5 690.3 605.9 400.2 675.2 646.3 Under 20 years ............ 040.3 882.7 635.0 607.5 757.1 702.8 650.2 432.9 20-24 years ............... 321.9 855.5 595.2 554.4 25-20 years ............... 430.4 741.1 586.0 031.3 504.4 449.9 440.8 30-34 years ................ 413.0 681.0 641.7 808.3 805.0 778.4 555.7 35 years and over .......... 351.0 813.5 1,273.7 1,133.5 1,049.1 1,112.1 595.1 a Rates per 100,000 live births.

216 <strong>Patterns</strong><strong>of</strong> Mortality in Childhood<br />

by Age <strong>of</strong> Mother in 15 Projects.<br />

TABLE 125. Deaths <strong>of</strong> Infants with Congenital Anomalies<br />

Under 20-24 25-29 30-34 35 years Unknown<br />

Total 20 years years years years a r<br />

Total ........................... 2,873 373 788 030 410 465 207<br />

ARGENTINA<br />

Chaco Province ............... .. 74 18 15 18 <br />

San Juan Province .............. 176 23 52 38<br />

BOLIVIA project................. 92 5 20 18 <br />

IRAZIL<br />

Recife ......................... 206 35 44 52 <br />

Ribeirao Prto.................. 101 5 <br />

SAo Paulo ...................... 458 39 <br />

CANADA<br />

11 11 1<br />

28 29 0<br />

13 21 15<br />

17 35 23<br />

30 20 11 17 12<br />

150 124 65 53 27<br />

10 21 2<br />

Shcrbrooke ..................... 124 7 47 31 <br />

CHILE project ................... 307 37 83 09 50 60 8<br />

COLOMBIA<br />

107 17 28 10 16<br />

12 15<br />

Call ........................... <br />

8 13 40<br />

Cartagena ..................... 110 10 21 18 <br />

28 10 17 32 10<br />

Medellln ....................... 126 20 <br />

EL SAIVAI)OR project .......... 210 38 03 35 36 42 2<br />

JAMAICA<br />

Kingston-St. Andrew............ 201 38 55 51 23 26 8<br />

MEXICO<br />

Monterrey ..................... 353 30 70 02 <br />

68 77 34<br />

UNITED STATES<br />

California project ............... 222 45 70 50 <br />

31 10 4<br />

similar to the percentage <strong>of</strong> live births projects were the rates for mothers aged 35<br />

among mothers 30 years and over in tile years and over higher than for mothers<br />

Chaco Province and Monterrey projects but under 20 years (Sherbrooke, Chile, El Salvahigher<br />

than that in the other five projects dor, and Monterrey). In Figure 108, the<br />

with maternal ages for live b6i.ths known rates with Down's disease excluded are<br />

(Table 148 <strong>of</strong> Chapter XII).<br />

Sllown by t broken linp. Some increase with<br />

The death rates in the seven projects for age remained in all four projects.<br />

which the distribution <strong>of</strong> live births by Although differences were noted, similarimothers'<br />

age were available are given in ties also were observed. For example, the<br />

Table 126 and in Figure 108. In only foul' death rates for the infants <strong>of</strong> young mothers<br />

TABLE 126.<br />

Mortality' <strong>of</strong> Infants with Congenitnl Anomalies by Age<br />

<strong>of</strong> Mother in Seven Projects.<br />

ARGEN-<br />

EL SAL-<br />

UNITED<br />

TINA BRAZIL CANADA CILE VADOIt MEXICO California<br />

STATES<br />

Age <strong>of</strong> mother Chaco Slo Paulo Sherbrooke project project AMonterrey<br />

Province<br />

project<br />

Total ..................... 420.5 787.5 <br />

730.7 704.5 690.3 605.9 400.2<br />

675.2 646.3<br />

Under 20 years ............ 040.3 882.7 635.0 607.5 757.1 <br />

702.8 650.2 432.9<br />

20-24 years ............... 321.9 855.5 595.2 554.4 <br />

25-20 years ............... 430.4 741.1 586.0 031.3 504.4 449.9 440.8<br />

30-34 years ................ 413.0 681.0 641.7 808.3 805.0 778.4 555.7<br />

35 years and over .......... 351.0 813.5 1,273.7 1,133.5 1,049.1 1,112.1 595.1<br />

a Rates per 100,000 live births.

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