BIBLIOGRAPHIC INPUT SHEET TEMPORARY Patterns of mortality ...

:202 ,Pattern8of Mortality in Childhood
Fia. 101. Mortality of Infants with Down's Dis- and Mexico City (160.3 and 177.1 per 100,­
ease as Underlying or Associated Cause in 15 Pro- 000 live births) were higher than those of
jects.DETSPt1000LVBITS00lvbitsweehgethntoef
jers.DATS0,o0 , LIVES,,, the Chile and Monterrey projects in the In-
0 ,o 80 10 vestigation (96.4 and 88.7, respectively).
., .Since many children with Down's disease do
- .. .not die in infancy, the findings in the WHO
_ ... .. . study could be expected to be higher than
MMio . . . .
those for deceased infants in the Investigo-
~ -
11111~19 0P~,0
tion.
Wit .In the age group 1-4 years 89 deaths were
soWJim OVU,
due to Down's disease as underlying or as­
110,PLO sociated cause. This represents 20.0 per
cent of the deaths with congenital anom-
SHmAOOoEa
oio nv ' alies in this age group. Medellin, which had
MUNIA9,10 M
one of the highest rates for this disease in
mm [ infancy, had the highest in this age group.
UNDELYING CAUSE ASSOCIATED CAUSE It is well known that older mothers are
more frequently the ones who have a child
Medellin and Sfio Paulo had rates similar with Down's disease. This was the case in
in size to those found in the WHO study the projects in the Investigation, as can be
(Stevenson et al., 1966) (Table 110). How- seen in Tables 113 and 114. Of the mothers
ever, the rates in that study for Santiago with ages known, 138 out of 289 (or 47.8 per
TALs 113. Deaths of Infants with Down's Disease as Underlying or Associated Cause by Age of Mother
in 15 Projects.
Project Total Under 20-24 25-20 UO-34 35 ?,cars Unknown
r0 years years years years an over
Total ............................ 306 20
39 40 52 138 17
ARGENTINA
Chaco Province ................. 8 - - - 1 6 1
San Juan Province .............. 14 - 2 3 1 8 -
BOLIVIA project ................ 7 ­ 3 1 2 1 -
BRAZIL
Recifo ......................... 19 1 1 2 2 12 1
Ribeirao Pr~to.................. 14 - 1 2 3 6 2
Sao Paulo ...................... 34 2 6 5 8
12 1
CANADA
Slherbrooke ..................... 8 - I - 1 6 ­
7 8 21 -
CHILE project ................... 42 2 4
COLOMBIA
Call ........................... 10 - 1 2 2 4 1
5
Cartagena ..................... 20 2 3 2 2 6
4 10 -
Medellin ....................... 19 3 1 1
EL SALVADOR project .......... 22 - 3 3 5 11 -
JAMAICA
Kingston-St. Andrew ............ 27 2 4 5 5 10 1
MEXICO
Monterrey ..................... 47 6 8 4
5 20 4
UNITED STATES
California project ............... 15 2 1
3 3 51