BIBLIOGRAPHIC INPUT SHEET TEMPORARY Patterns of mortality ...

ChapterX. CongenitalAnomalies
201
111). An explanation for this high propor- tional anomalies of other systems. Those
tion may be the completeness of the infor- most frequently found were in the muscumation
recorded. In five other projects at loskeletal system: a total of 110, or 21.5 per
least one-third of the deceased infants with 100 deaths of infants with anomalies of the
anomalies of the nervous system had addi- nervous system.
DOWN'S DISEASE
Down's disease (trisomy 21) is a severe derlying cause and in 220 associated cause
developmental disease affecting various sys- (Table 112). As can be seen, use of the untems
and characterized by the presence of derlying cause alone would provide inforinaan
extra, sinal! chromosome conventionally tion on only 28.1 per cent of these deaths.
termed No. 21. This congenital anomaly for The total rates in infancy varied from a low
which methods of prevention are currently of 18.6 per 100,000 live births in the Bolivia
being recommended is of special interest at project to 111.7 in Cartagena (Figure 101).
this time.
The rates as underlying cause were highest
In the 15 projects there were 306 infant in the two projects with the highest total
deaths clue to this disease; in 86 it was un- rates (Cartagena and Medellin).
TABLE 112.
Down's Disease as Underlying or Assoialed Cause of Death' in Children Under 5 Years,
in Two Age Groups, in 15 Projects.
Total Underlying Associated Total Underlying Associated
Project No. Rate No. Hate No. lIate No. Ralte No. Itate No. Rate
Under I year
1-4 years
Total .................... ............ 306 14.6 86 18.1 220• 46.4 89 5.1 35 2.1 54 3.3
ARGENTINA
Chaco Province ...................... 8 45.5 4 22.7 .I 22.7 4 6.6 4 6.6 - -
San Juan Province .................... 14 50.9 2 8.0 12 51.4 .I 4.8 - - 4 4.8
BOI.IVIA project ...................... 7 18.0 I 2.7 6 16.0 1 2 1.6 - - 2 1.0
BRAZIL
Recife .............................. 1 62.5 3 9.9 16 52.6 3 3.1 I 1.0 2 2.1
fibeirfio Prato ....................... 14 70.8 5 27.4 9 411.3 4 0.1 2 3.1 2 3.1
Sao Paulo ........................... 34 58.5 I1 18.9 23 39.5 9 4.8 2 1.1 7 3.7
CANADA
Sherbrooke ......................... 8 47.1 1 5.9 7 41.2 4 5.4 4 5.4 - -
CHILE project ........................ 42 06.4 15 34..4 27 62.0 11 6.0 5 3.0 6 3.6
COLOMIBIA
Cali ....... ........................ 10 ,17.4 1 4.7 9 .12.7 5 6.2 - - 5 6.2
Cartagena ........................... 20 111.7 8 44.7 12 67.0 5 7.3 2 2.0 3 4.4
Medellin ........................... 19 07.0 9 46.4 10 51.5 0 12.1 3 4.0 6 8.0
EL SALVADOR project ................ 22 70.0 5 16.1 17 54.8 5 5.2 3 3.1 2 2.1
JAMAICA
I
Kingston-St. Andrew ................. 27 65.0 6 14.6 21 51.3 13 9.1 a 4.2 7 4.0
IEXICO
Monterrey ........................... 47 88.7 12 22.6 35 66.0 0 3.5 1 0.6 5 2.0
UNITED STATES
California project ..................... 15 33.5 3 6.7 12 20.8 5 3.1 2 1.2 3 1.9
Rates under 1 year of ago per 100,000 live births; others per 100,000 population.