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BIBLIOGRAPHIC INPUT SHEET TEMPORARY Patterns of mortality ...

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190 <strong>Patterns</strong><strong>of</strong> Mortalityin Childhood<br />

Fia. 97. Mortality <strong>of</strong> Children 1-4 Years <strong>of</strong> Age<br />

with Congenital Anomalies as Underlying or Associated<br />

Causes or as Minor Anomalies in 15 Projects.<br />

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CAUSE CAUSE ANOMALY<br />

genital hernias as well as a few other anomalies<br />

have been added to those in Section<br />

XIV. However, these additions are not sufficient<br />

to explain the differences between the<br />

data for the countries as a whole and those<br />

for the projects. The findings <strong>of</strong> the Investigation<br />

are probably more complete than the<br />

information hitherto available.<br />

Of the 7,493 deceased children 1-4 years<br />

<strong>of</strong> age, 444 or 5.9 per cent were found to<br />

have at least one anomaly, which gave a<br />

rate <strong>of</strong> 26.9 per 100,000 population in that<br />

age group. The variation was from 18.8 to<br />

61.7 per 100,000 (Figure 97) in 14 <strong>of</strong> the<br />

projects. As in the case <strong>of</strong> infants, the death<br />

rate in Bolivia was very low (11.4). The<br />

comparison <strong>of</strong> the 1967 rates as underlying<br />

causes for five countries (WHO, 1971) and<br />

for the seven projects <strong>of</strong> the Investigation<br />

is as follows:<br />

WHO data, 1967<br />

Investigation<br />

Canada 12.5 Sherbrooke 9.4<br />

Chile 5.9 Chile project 17.9<br />

Colombia 5.4 Cali 14.8<br />

Cartagena 20.3<br />

Medellin 28.2<br />

Mexico 4.1 Monterrey 15.3<br />

United States 9.7 California project 13.7<br />

The rates obtained in the Investigation<br />

in this age period were higher in all projects<br />

except that in Sherbrooke. (The experience<br />

in that project was small, and variations<br />

would be expected to occur from year to<br />

year; there were only seven deaths <strong>of</strong> children<br />

1-4 years <strong>of</strong> age with an anomaly as<br />

underlying cause.) The findings <strong>of</strong> the Investigation<br />

are providing more complete and<br />

reliable information regarding the important<br />

problem <strong>of</strong> congenital anomalies than<br />

that available from the <strong>of</strong>ficial reports <strong>of</strong><br />

countries.<br />

DIAGNOSTIC EVIDENCE<br />

The completeness <strong>of</strong> the information on<br />

congenital anomalies depends in part on the<br />

diagnostic evidence available. Table 102<br />

shows the type <strong>of</strong> evidence obtained for the<br />

anomalies assigned as underlying causes <strong>of</strong><br />

death in 1,948 infants and children 1-4<br />

years <strong>of</strong> age. Out <strong>of</strong> this number, autopsies<br />

had been performed on 544 or 27.9 per cent,<br />

a proportion that was much higher than<br />

that for deaths from all causes (16.9 per<br />

cent). Clinical information only was available<br />

for 64.7 per cent. Relatively few anomalies<br />

were included as underlying causes on<br />

the basis <strong>of</strong> medical interviews only (80

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