XANTHOMA OF THE BREAST In a series of nine hundred (circa ...

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American Association for Cancer Research.
XANTHOMA OF THE BREAST nOI
radical mastectomy performed. The section showed "large polyhedral
cells apparently lying in alveoli. These cells were not
quite like the usual type of carcinoma, being even larger than the
unshrunk cells seen in fresh sections; but the appearance was not
recognizable as anything else, and the diagnosis was taken to be
confirmed." The case of traumatic fat necrosis (Case 6) included
in the present study was diagnosed by frozen section.
SUMMARY
Xanthomas in general have been discussed, and tumors of the
breast containing xanthoma cells have been classified as follows:
A. Primary xanthoma: a very rare tumor composed wholly of
xanthoma cells and arising as a local manifestation of the
syndrome of xanthomatosis.
B. Secondary xanthomatous degeneration, frequently encountered in
(1) true neoplasms, (2) inflammatory processes, and (3)
traumatic fat necrosis.
Three cases of primary xanthoma of the breast, and illustrative
cases of secondary xanthomatous degeneration occurring in fibroadenoma,
in chronic breast abscess, and in traumatic fat necrosis in
the breast have been described.
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