Differential Diagnosis of Dementias - Alzheimer's Association
Differential Diagnosis of Dementias - Alzheimer's Association
Differential Diagnosis of Dementias - Alzheimer's Association
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Core<br />
Clinical<br />
Behavioral Variant <strong>of</strong> Frontal Temporal<br />
Dementia<br />
• Progressive deterioration <strong>of</strong> behavior<br />
and/or cognition with ≥ 3 early: 1<br />
– Behavioral disinhibition<br />
– Apathy<br />
– Loss <strong>of</strong> sympathy/empathy<br />
– Perseverative, stereotyped or<br />
compulsive behavior<br />
– Hyperorality<br />
– Executive deficits with relative<br />
sparing <strong>of</strong> memory and visuospatial<br />
function<br />
• Frontal and/or anterior temporal<br />
atrophy on MRI or CT 1<br />
• Tactless and impulsive behavior 2,3<br />
1. Rascovsky K, Hodges JR, Knopman D, et al. Brain. Sep 2011;134(Pt 9):2456-2477. 2. Neary D, Snowden JS, Gustafson L, et al. Neurology. Dec 1998;51(6):1546-1554. 3.<br />
McKhann GM, Albert MS, Grossman M, et al. Arch Neurol. Nov 2001;58(11):1803-1809.<br />
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