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Differential Diagnosis of Dementias - Alzheimer's Association

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Core<br />

Clinical<br />

Vascular Dementia<br />

• Decline in cognitive function from a<br />

prior baseline and a deficit in<br />

performance in ≥2 1<br />

– Executive/attention<br />

– Memory (may not always be impaired) 2<br />

– Language<br />

– Visuospatial function<br />

• Evidence <strong>of</strong> cerebrovascular<br />

disease via neuroimaing 1,3,4<br />

• Focal neurological signs that<br />

may relate to vascular lesion<br />

location 1,3,4<br />

• Cognitive deficits may occur in<br />

a stepwise fashion 1,3,4<br />

1. Gorelick PB, Scuteri A, Black SE, et al. Stroke. Sep 2011;42(9):2672-2713. 2. Szoeke CE, Campbell S, Chiu E. Vascular Cognitive Disorder. In: Weiner MF,<br />

Lipton AM, eds. Textbook <strong>of</strong> Alzheimer disease and other dementias. Washington, DC: American Psychiatric Pub.; 2009. 3. American Psychiatric <strong>Association</strong>.<br />

Diagnostic and Statistical Manual <strong>of</strong> Mental Disorders. Fourth Edition. Text Revision. (DSM-IV-TR ® .) Washington, DC: American Psychiatric <strong>Association</strong>; 2000.<br />

22<br />

4. Roman GC, Tatemichi TK, Erkinjuntti T, et al. Neurology. Feb 1993;43(2):250-260.

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