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Differential Diagnosis of Dementias - Alzheimer's Association

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Core<br />

Clinical<br />

Alzheimer’s Dementia<br />

• Multiple cognitive deficits, consisting <strong>of</strong><br />

memory impairment and ≥1 1<br />

– Aphasia<br />

– Apraxia<br />

– Agnosia<br />

– Executive function<br />

• Each deficit causes significant impairment<br />

in social or occupational functioning 1<br />

Language<br />

Praxis<br />

Gnosis<br />

• Difficulty learning and remembering<br />

new information 2<br />

• Repetitiveness, anomia 2<br />

• Poor orientation to time 2<br />

AD largely<br />

involves<br />

temporalparietal<br />

deficits 3<br />

1. American Psychiatric <strong>Association</strong>. Diagnostic and Statistical Manual <strong>of</strong> Mental Disorders. Fourth Edition. Text Revision. (DSM-IV-TR ® .) Washington, DC: American<br />

Psychiatric <strong>Association</strong>; 2000. 2. Geldmacher D. Alzheimer’s Disease. In: Weiner MF, Lipton AM, eds. Textbook <strong>of</strong> Alzheimer disease and other dementias. 1st ed.<br />

Washington, DC: American Psychiatric Pub.; 2009. 3. Tarawneh R, Galvin JE. Dementia with Lewy Bodies and other Synucleinopathies. In: Weiner MF, Lipton AM,<br />

eds. Textbook <strong>of</strong> Alzheimer disease and other dementias. 1st ed. Washington, DC: American Psychiatric Pub.; 2009.<br />

19

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