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Differential Diagnosis of Dementias - Alzheimer's Association

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Delirium, Dementia, and Depression 1,2<br />

Delirium Dementia Depression<br />

Onset Sudden Insidious Recent or recurrent<br />

Duration<br />

Minutes to<br />

days<br />

Months to years<br />

Weeks to months<br />

Progression<br />

Reversible –<br />

resolves with<br />

treatment<br />

Irreversible<br />

Reversible, relapses<br />

common<br />

Consciousness Fluctuating Generally alert<br />

Generally alert,<br />

possibly withdrawn<br />

History <strong>of</strong><br />

depression<br />

Usually<br />

negative<br />

Usually negative<br />

Usually positive<br />

Visuospatial Preserved Often abnormal Preserved<br />

Mood – Sadness/<br />

Guilt/Worthlessness<br />

Absent Usually absent Usually Present<br />

1. Cefalu C, Grossberg GT. Leawood, KS: American Academy <strong>of</strong> Family Physicians; 2001. 2. American Psychiatric <strong>Association</strong>. DSM-IV-TR ® .<br />

Washington, DC: American Psychiatric <strong>Association</strong>; 2000.<br />

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