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2000 HSS/PSA Program 1 - History of Science Society

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<strong>PSA</strong> Abstracts<br />

thesis, suggested by Kevin Hoover, that causal relations among “concrete”<br />

variables are fundamental.<br />

Brian Haynes McMaster University<br />

What kind <strong>of</strong> evidence is it that evidence based medicine advocates want<br />

patients, practitioners, policy makers and the public to pay attention to?<br />

Advocates <strong>of</strong> evidence based medicine (EBM) want health care providers and<br />

consumers to pay attention to the best findings from health care research that<br />

are both valid and ready for clinical application concerning the cause, course,<br />

diagnosis, prevention and treatment <strong>of</strong> disease. EBM claims that practitioners<br />

can know what are valid and best practices through understanding recently<br />

developed applied research methods (from the second half <strong>of</strong> the 20th century)<br />

and using this understanding to judge studies published in the medical literature.<br />

In doing so, EBM advocates have proclaimed a new paradigm, that was initially<br />

and provocatively pitted against traditional medicine, in which the key elements<br />

<strong>of</strong> knowing for clinical purposes are understanding <strong>of</strong> basic pathophysiologic<br />

mechanisms <strong>of</strong> disease coupled with clinical experience. This initial conception,<br />

that EBM is attempting to replace traditional medicine, should to be put to<br />

rest: EBM is attempting to augment rather than replace individual clinical<br />

experience (which EBM sees as necessary but insufficient to provide best<br />

care) with newly derived facts from science that are demonstrably by the new<br />

methods <strong>of</strong> health care research valid and ready for clinical application. These<br />

methods reduce bias and eliminate many possible alternative explanations for<br />

studies intended to provide clear answers about the nature, detection, and<br />

management <strong>of</strong> health care problems. EBM raises a number <strong>of</strong> issues that<br />

have come to the attention <strong>of</strong> philosophers <strong>of</strong> science, including what constitutes<br />

best evidence, whether EBM has gone s<strong>of</strong>t in trying to accommodate research<br />

designs other than its gold standard <strong>of</strong> the randomized controlled trial, and<br />

whether its approach to methodology is explicable by disunity <strong>of</strong> science<br />

advocates, or in need <strong>of</strong> a major revision to unify its approach. Also <strong>of</strong> interest<br />

are questions <strong>of</strong> whether what one learns from groups <strong>of</strong> patients in relatively<br />

contrived research settings can be applied to individuals in usual clinical<br />

circumstances. Moral philosophers have taken less interest, but it may be that<br />

the ethical issues raised by EBM are even more important, especially dilemmas<br />

in distributive justice and prolonging life into the realm <strong>of</strong> misery and beyond<br />

the point <strong>of</strong> senescence.<br />

220

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