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Listing of Sessions and Abstracts of Papers - History of Science ...

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Waller, John<br />

E-mail Address: jwaller1@hotmail.com<br />

Protecting the Lineage: Doctors, Disease <strong>and</strong> Nineteenth-Century Marital Advice<br />

Belief in the heritability <strong>of</strong> chronic maladies such as scr<strong>of</strong>ula, gout, consumption <strong>and</strong> insanity<br />

achieved the status <strong>of</strong> a core paradigmatic assumption among doctors <strong>of</strong> the early nineteenth century.<br />

These supposedly hereditary diseases were commonly described as highly resistant to therapeutic intervention<br />

<strong>and</strong> likely to entail on subsequent generations lives <strong>of</strong> suffering <strong>and</strong> stigmatization. Reflecting<br />

on this, most medical writers who wrote on the theme <strong>of</strong> inherited malady concurred in reproving the<br />

marriage <strong>of</strong> anyone carrying hereditary taints. Those who eschewed medical advice <strong>and</strong> had children<br />

with the consumptive, insane or scr<strong>of</strong>ulous were also roundly condemned by doctors for irresponsibility<br />

<strong>and</strong> callous egoism. In scores <strong>of</strong> advice manuals, the necessity for marital decisions to be grounded in<br />

physiology as much as economics <strong>and</strong> aesthetics was repeatedly extolled. And by the middle decades <strong>of</strong><br />

the century, debate as to the propriety <strong>of</strong> avoiding marriages with the hereditarily ill had emerged as a<br />

powerful medical discourse. Not least because these medical injunctions have been almost entirely<br />

overlooked by historians, the aims <strong>of</strong> this paper are to trace how medical ideas <strong>of</strong> hereditary disease<br />

were disseminated into the public sphere <strong>and</strong> how, once there, they impacted upon reproductive thought<br />

<strong>and</strong> behavior. Concentrating on medical advice manuals written for a wide audience, I will also consider<br />

the strategic underpinnings <strong>of</strong> the increasing stress placed by nineteenth-century doctors on the subject<br />

<strong>of</strong> heredity disease; the receptivity <strong>of</strong> the public to medical hereditarianism; <strong>and</strong>, finally, the broader<br />

implications this discourse had for the later emergence <strong>of</strong> organized eugenics movements in both Britain<br />

<strong>and</strong> America.<br />

Watkins, Elizabeth<br />

E-mail Address: ewatkins@<strong>and</strong>rew.cmu.edu<br />

<strong>Science</strong> Confronts Aging: The Case <strong>of</strong> Hormone Replacement Therapy<br />

This paper explores the role <strong>of</strong> scientists in the successful marketing <strong>of</strong> hormone replacement therapy<br />

to older women <strong>and</strong> their physicians. In the mid to late 1970s, the fate <strong>of</strong> estrogen replacement therapy<br />

was very much in question, because scientific studies had demonstrated that estrogen use increased the<br />

risk <strong>of</strong> endometrial cancer. In the 1980s, however, laboratory, clinical, <strong>and</strong> epidemiological data helped<br />

to revive the popularity <strong>of</strong> hormone replacement for postmenopausal women, by demonstrating that this<br />

drug therapy could prevent, or at least forestall, the development <strong>of</strong> osteoporosis. Pharmaceutical manufacturers<br />

used scientific studies to recapture the market for hormone replacement, by advertising the<br />

drugs' alleged long-term health benefits. The exp<strong>and</strong>ed recommendation for prescribing hormone<br />

therapy to prevent osteoporosis in older women was based on scientific studies that convinced both<br />

government advisors <strong>and</strong> practicing physicians <strong>of</strong> the validity <strong>of</strong> estrogen's protection against bone loss.<br />

These investigations - some carefully conceived <strong>and</strong> carried out, others sloppily designed <strong>and</strong> executed -<br />

were highly valued <strong>and</strong> influential in shifting the pendulum <strong>of</strong> approval toward long-term use <strong>of</strong> hormone<br />

therapy. In the late 20th century, doctors increasingly relied on laboratory scientists to help them<br />

make diagnoses (witness the pr<strong>of</strong>usion <strong>of</strong> laboratory tests) <strong>and</strong> determine treatments (thanks to the<br />

multitude <strong>of</strong> new drugs flowing from academic <strong>and</strong> industrial labs). In this paper, I argue that the prescription<br />

<strong>and</strong> use <strong>of</strong> hormone replacement drugs were influenced by the increasingly authoritative voices<br />

<strong>of</strong> laboratory <strong>and</strong> epidemiological researchers, even though their results were not only contradictory, but<br />

also difficult to interpret.<br />

Weikart, Richard<br />

E-mail Address: rweikart@toto.csustan.edu

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