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Abstracts of the History of Science Society 2004 Austin Meeting 18 ...

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tions it raised were not resolved ei<strong>the</strong>r by Galileo or by <strong>the</strong> court, and that <strong>the</strong>y remain relevant to modern debates about <strong>the</strong> use <strong>of</strong><br />

both copyright and patents to protect intellectual property claims in scientific findings.<br />

Christina Brandt, Max Planck Institute for <strong>the</strong> <strong>History</strong> <strong>of</strong> <strong>Science</strong> (brandt@mpiwg-berlin.mpg.de)<br />

Friday, 19-Nov-04, 9:00 - 11:45 AM - Big Bend D & E<br />

Between Fact and Fiction: Bioscientific Research and Early Debates About Cloning and Genetic Engineering in Germany<br />

This paper analyzes scientific and cultural layers in <strong>the</strong> history <strong>of</strong> cloning. It addresses <strong>the</strong> relationship between bioscientific research,<br />

popular representations and public debates that flourished around <strong>the</strong> figure <strong>of</strong> <strong>the</strong> “clone”. The focus will be on <strong>the</strong> life sciences in<br />

Germany from <strong>the</strong> late 1960s to <strong>the</strong> early 1980s. This period can be characterized by two major scientific events: First, John Gurdon´s<br />

(Oxford) success in cloning frogs in <strong>the</strong> early 1960s gave rise to fantastical representations around <strong>the</strong> figure <strong>of</strong> <strong>the</strong> “clone”. Second,<br />

<strong>the</strong>se popular debates about cloning experienced both <strong>the</strong>ir highpoint and a temporary halt in <strong>the</strong> early 1980s when Karl Illmensee<br />

(Geneva) announced that he was able to clone mice but shortly afterwards his claims were disproved. In <strong>the</strong> first part <strong>of</strong> <strong>the</strong> paper, I<br />

will follow scientific developments in German developmental biology by focussing on research at <strong>the</strong> Friedrich Miescher Laboratorium<br />

<strong>of</strong> <strong>the</strong> Max Planck <strong>Society</strong> in Tuebingen. The second part will examine <strong>the</strong> public debates about cloning and genetic engineering in<br />

Germany with attention given to <strong>the</strong> demarcation between scientific facts and popular fiction. By comparing <strong>the</strong>se German developments<br />

to those in <strong>the</strong> United States and Great Britain, <strong>the</strong> paper will try to specify at which level national peculiarities played a part in<br />

an internationally organized scientific landscape building up in <strong>the</strong> second half <strong>of</strong> <strong>the</strong> 20th century.<br />

Sabine Brauckmann, KLI (sabine.brauckmann@kli.ac.at)<br />

Friday, 19-Nov-04, 1:30 - 3:10 PM - Texas Ballroom VI<br />

‘’Cells Migrate and Shape’’: A Historical Sketch <strong>of</strong> Developmental Fate Maps<br />

My talk presents a historical chapter <strong>of</strong> developmental physiology by focusing on Walter Vogt (<strong>18</strong>88-1941) and Sven Hörstadius (<strong>18</strong>98-<br />

1996), two experimental biologists, and on two conceptions, namely <strong>the</strong> gastrea <strong>the</strong>ory and <strong>the</strong> gradient notion. Fur<strong>the</strong>r, I want to show<br />

(1) how developmental physiology depicted <strong>the</strong> migration and shaping <strong>of</strong> cells during gastrulation in fate maps and (2)how <strong>the</strong> gradient<br />

concept as formulated by Boveri was finally confirmed. The crucial issue comparative anatomy and embryology tried to solve around<br />

<strong>18</strong>80 was how <strong>the</strong> mesoderm forms and whe<strong>the</strong>r it proceeds by invagination or delamination. However, it was difficult to reconstruct<br />

<strong>the</strong>se morphogenetic movements by observing whole or sectioned embryos alone. Besides an experimental turn, technical improvements<br />

like micrometer, vital staining methods, and apochromatic objectives helped to label <strong>the</strong> cells <strong>of</strong> <strong>the</strong> three germ layers and to follow<br />

<strong>the</strong>ir fate at successive intervals during gastrulation. By <strong>the</strong>se new methods, <strong>the</strong> classical disciplines slowly overcame <strong>the</strong>ir descriptive<br />

state and moved towards <strong>the</strong> more dynamical representation <strong>of</strong> developmental mechanics. In <strong>the</strong> 1920s Vogt perfected <strong>the</strong> staining<br />

method and constructed more or less idealized fate maps <strong>of</strong> <strong>the</strong> toad Bombinator. For him, <strong>the</strong> results corroborated Haeckel’s gastrea<br />

<strong>the</strong>ory. Vogt’s research revolutionized comparative embryology and formed <strong>the</strong> basis for interpreting developmental physiology. A few<br />

years later Hörstadius embarked on an experimental program with sea urchins hoping to solve <strong>the</strong> question <strong>of</strong> <strong>the</strong> temporal determination<br />

<strong>of</strong> invagination. His main objective was to improve on <strong>the</strong> data <strong>of</strong> Morgan and Driesch who had estimated <strong>the</strong> invaginating material<br />

by counting nuclei. With his technique <strong>of</strong> fine glass needles and Vogt’s staining method, Hörstadius could now trace <strong>the</strong> fate <strong>of</strong> <strong>the</strong><br />

various cell groups into <strong>the</strong> later larva at <strong>the</strong>ir exact temporal determination. His data corrected <strong>the</strong> old invagination explanation <strong>of</strong> gastrulation<br />

and secured <strong>the</strong> gradient concept. Besides <strong>the</strong> narrative <strong>of</strong> developmental fate mapping, my main objective is to demonstrate<br />

<strong>the</strong> conceptual difference in <strong>the</strong>ir research programs. For, Vogt’s work was firmly rooted in homology studies <strong>of</strong> <strong>the</strong> 19th century whereas<br />

Hörstadius concentrated on embryonic cells and intercellular communication.<br />

Richard Burkhardt, University <strong>of</strong> Illinois, Urbana-Champaign (burkhard@uiuc.edu)<br />

Saturday, 20-Nov-04, 3:30 - 5:30 PM - Texas Ballroom VI<br />

Ordering and Coordinating Naturalists’ Practices in Restoration France<br />

The distinction between <strong>the</strong> naturalist voyager and <strong>the</strong> cabinet naturalist predates but does not map seamlessly onto <strong>the</strong> later contrast<br />

between <strong>the</strong> field naturalist and <strong>the</strong> lab or museum worker. One reason for this is that <strong>the</strong> primary task <strong>of</strong> naturalist voyagers, at least<br />

as conceived by those who most <strong>of</strong>ten sponsored <strong>the</strong>ir travels, was to collect specimens for study and display back in museums, not to<br />

pursue field studies as such. In <strong>the</strong> years immediately after <strong>the</strong> Napoleonic Wars, <strong>the</strong> National Museum <strong>of</strong> Natural <strong>History</strong> in Paris made<br />

special efforts to encourage <strong>the</strong> collecting efforts <strong>of</strong> travelers, colonial <strong>of</strong>ficials, sea captains, and, most notably, a select number <strong>of</strong> individuals<br />

whom <strong>the</strong> Museum paid to be naturalist voyagers. The present paper looks at <strong>the</strong> naturalist voyagers on <strong>the</strong> Museum’s payroll<br />

from <strong>18</strong>15 to <strong>18</strong>30, examining in particular <strong>the</strong> ways in which <strong>the</strong>ir own interests and <strong>the</strong>ir actual practices in <strong>the</strong> field corresponded to<br />

or diverged from <strong>the</strong> aims <strong>of</strong> <strong>the</strong> institution that sponsored <strong>the</strong>m.<br />

D. Graham Burnett, Princeton University (dburnett@princeton.edu)<br />

Saturday, 20-Nov-04, 9:00 - 11:45 AM - Texas Ballroom III<br />

Whales and <strong>the</strong> Cold War: The First International Symposium on Cetacean Research<br />

From <strong>the</strong> 15th to <strong>the</strong> <strong>18</strong>th <strong>of</strong> August, 1963, more than fifty scientists from around <strong>the</strong> world ga<strong>the</strong>red in <strong>the</strong> “John Glenn Suite” <strong>of</strong> <strong>the</strong>

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