alzheimer: 100 years and beyond - Hertie-Institut für klinische ...
alzheimer: 100 years and beyond - Hertie-Institut für klinische ...
alzheimer: 100 years and beyond - Hertie-Institut für klinische ...
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ALZHEIMER: <strong>100</strong> YEARS AND BEYOND<br />
www.alz<strong>100</strong>.de<br />
SPEAKERS INCLUDE:<br />
K. Ashe, USA<br />
K. Beyreuther, Germany<br />
H. Braak, Germany<br />
M. Breteler, Netherl<strong>and</strong>s<br />
J.-P. Brion, Belgium<br />
M. Citron, USA<br />
P. Davies, USA<br />
M. De Leon, USA<br />
B. De Strooper, Belgium<br />
N. Fox, UK<br />
B. Frangione, USA<br />
A. Goate, USA<br />
M. Goedert, UK<br />
T. Golde, USA<br />
C. Haass, Germany<br />
J. Hardy, USA<br />
M. Hutton, USA<br />
B. Hyman, USA<br />
Y. Ihara, Japan<br />
K. Iqbal, USA<br />
T. Iwatsubo, Japan<br />
Z. Khachaturian, USA<br />
W. Klunk, USA<br />
V. Lee, USA<br />
E. M<strong>and</strong>elkow, Germany<br />
C. Masters, Australia<br />
J. Morris, USA<br />
R. Nitsch, Switzerl<strong>and</strong><br />
S. Paul, USA<br />
D. Price, USA<br />
A. Roses, USA<br />
T. Saido, Japan<br />
G. Schellenberg,USA<br />
D. Schenk, USA<br />
D. Selkoe, USA<br />
S. Sisodia, USA<br />
P. St. George-Hyslop, Canada<br />
R. Tanzi, USA<br />
R. Terry, USA<br />
L. Thal, USA<br />
J. Trojanowski, USA<br />
C. Van Broeckhoven, Belgium<br />
B. Winblad, Sweden<br />
M. Wolfe, USA<br />
C. Wong, USA<br />
B. Yankner, USA<br />
S. Younkin, USA<br />
centenary meeting<br />
november 2 – 5, 2006<br />
tübingen, germany<br />
organized by M. Jucker, K. Beyreuther, G. Buchkremer,<br />
Y. Christen, C. Haass, K. Maurer,<br />
J. Mervaillie, R. Nitsch
Alzheimer: <strong>100</strong> Years <strong>and</strong> Beyond<br />
centenary meeting<br />
november 2 - 5, 2006<br />
tübingen, germany<br />
On November 3, 1906 Alois Alzheimer travelled to the university city of Tübingen,<br />
Germany to present an unusual case of dementia. Auguste D. would become<br />
known as the first documented case of Alzheimer’s disease (AD) – a disorder of the<br />
brain's nerve cells that impairs memory, cognition <strong>and</strong> behavior. AD is widely known<br />
today as the most common form of dementia, which currently affects about 20<br />
million people worldwide. Alois Alzheimer described the pathological<br />
characteristics of the disease in the auditorium of the Clinic for Psychiatry at the<br />
University of Tübingen, the same location where we will mark this milestone’s <strong>100</strong>-<br />
year anniversary on November 2-5, 2006.<br />
This historic event will begin in the evening of November 2 with an opening session<br />
for the public. November 3 will be a retrospective day featuring «pioneers» who<br />
contributed to AD research over the last <strong>100</strong> <strong>years</strong>. On November 4, leading<br />
scientists will present in the morning «current concepts in AD research» <strong>and</strong> will<br />
discuss in the afternoon the most important «challenges for the new century of AD<br />
research». Attendees of the meeting will have the possibility to look at the original<br />
histological sections through the microscope of Alois Alzheimer, <strong>and</strong> the way they<br />
were projected. On November 5, there will be the possibility to visit Marktbreit, the<br />
charming birthplace of Alois Alzheimer where his life <strong>and</strong> tremendous scientific work<br />
can be appreciated. Because of space limitations in these historic buildings, the<br />
meeting must be limited to 200 people.<br />
To mark this historic event, a well documented book about the achievements in AD<br />
research from 1906-2006 with an outlook into the new century will be published at<br />
the time of the symposium.<br />
ALZHEIMER: <strong>100</strong> YEARS AND BEYOND<br />
centenary meeting • november 2 – 5, 2006, tübingen, germany
We expect significant media attention from Germany <strong>and</strong> abroad in response to<br />
this symposium. The meeting has also been selected as one of the «365 Places in<br />
the L<strong>and</strong> of Ideas», a project organised by the German government on the<br />
occasion of the 2006 Football World Championship in Germany. The AD centenary<br />
meeting will serve as a powerful retrospective as well as a forward-reaching<br />
gathering of experts, <strong>and</strong> will also provide an opportunity to promote awareness<br />
<strong>and</strong> funding of AD research <strong>and</strong> related neurodegenerative disease into the next<br />
century. In Germany <strong>and</strong> most other industrialized societies the number of people<br />
over 65 <strong>years</strong> of age is projected to increase 25-30% by 2030 with a dramatic<br />
increase in the incidence of age-related neurodegenerative diseases – making<br />
research <strong>and</strong> political awareness for the expected social <strong>and</strong> economical burden<br />
more essential than ever before.<br />
Such a meeting requires substantial logistic <strong>and</strong> financial support. We already have<br />
the support of the Ipsen Foundation in Paris who are also instrumental in organizing<br />
the event. Morever, we receive support from the Breuer Foundation <strong>and</strong> <strong>Hertie</strong><br />
Foundation in Frankfurt, the German Research Foundation, <strong>and</strong> various other<br />
donators, whose contributions are greatly appreciated. We are, however, looking<br />
for additional help to support this special event.<br />
The local organization commmittee<br />
Mathias Jucker, Jacqueline Mervaillie, Yves Christen, Konrad Beyreuther, Christian<br />
Haass, Konrad Maurer, Roger Nitsch, Gerhard Buchkremer<br />
The scientific advisory board<br />
Karen Ashe, Konrad Beyreuther, Heiko Braak, Jean-Pierre Brion, Yves Christen, Martin<br />
Citron, Carl Cotman, Mony De Leon, Bart De Strooper, Monica Di Luca, Karen Duff,<br />
Falk Fahrenholz, Blas Frangione, Dora Games, Sam G<strong>and</strong>y, Michel Goedert, Paul<br />
Greengard, John Growdon, Christian Haass, John Hardy, Jean-Jacques Hauw, David<br />
Holtzman, Michael Hutton, Bradley Hyman, Yasuo Ihara, Khalid Iqbal, Takeshi<br />
Iwatsubo, Mathias Jucker, Zaven Khachaturian, June Kinoshita, Eddie Koo, Frank<br />
LaFerla, Peter Lansbury, Lars Lannfelt, Virginia Lee, Eva M<strong>and</strong>elkow, Eckard<br />
M<strong>and</strong>elkow, Eliezer Masliah, Colin Masters, Mark Mattson, Konrad Maurer, Patrick<br />
McGeer, Roger Nitsch, Margaret Pericak-Vance, George Perry, Don Price, Allen<br />
Roses, Gerard Schellenberg, Dale Schenk, Dennis Selkoe, Sam Sisodia, Peter St.<br />
George-Hyslop, Gabrielle Strobel, Rudy Tanzi, Robert Terry, Leon Thal, John<br />
Trojanowski, Christine Van Broeckhoven, Bengt Winblad, Michael Wolfe, Bruce<br />
Yankner, Steve Younkin.<br />
ALZHEIMER: <strong>100</strong> YEARS AND BEYOND<br />
centenary meeting • november 2 – 5, 2006, tübingen, germany
Timetable<br />
Thursday, November 2, 2006<br />
18.00 Public Session in German:<br />
<strong>100</strong> Jahre Alzheimer Krankheit<br />
Welcome <strong>and</strong> moderation: Mathias Jucker<br />
<strong>Hertie</strong> <strong>Institut</strong>e for Clinical Brain Research, Tübingen<br />
Program<br />
- Aging <strong>and</strong> Alzheimer - a politician’s view:<br />
Erwin Teufel (former Prime Minister of Baden-Württemberg)<br />
- Alois Alzheimer - a historical view: Konrad Maurer (University of Frankfurt)<br />
- Aging <strong>and</strong> Alzheimer - a scientist's view: Konrad Beyreuther (State Secretary)<br />
- Aging <strong>and</strong> Alzheimer - an author's view: Martin Suter (author of Small World)<br />
- Aging <strong>and</strong> Alzheimer - a theologian's view: Hans Küng (Weltethos)<br />
21.00 Theater play about the life <strong>and</strong> work of Alois Alzheimer<br />
For further information please see<br />
www.oeffentliche_veranstaltung.html<br />
Friday, November 3, 2006<br />
9.00 – 17.00 Scientific Meeting<br />
Session 1: The Pioneers & The Beginning<br />
20.00 Theater (reserved for the symposium participants)<br />
Saturday, November 4, 2006<br />
9.00 – 16.00 Scientific Meeting<br />
Session 2: Current concepts<br />
Session 3: Challenges for the Future<br />
20.00 Conference Dinner<br />
Sunday, November 5, 2006<br />
Optional visit to Marktbreit, the birth place of Alois Alzheimer<br />
ALZHEIMER: <strong>100</strong> YEARS AND BEYOND<br />
centenary meeting • november 2 – 5, 2006, tübingen, germany
Speakers<br />
The following speakers were selected by voting of the Scientific Advisory Board <strong>and</strong><br />
have confirmed their participation.<br />
The Pioneers:<br />
Session 1<br />
The Pioneers & The Beginning<br />
R. Terry, USA (will also present the contributions of<br />
G. Blessed, A. Brun, J. A. N. Corsellis, P. Divry, D. A. Drachman, N.K. Gonates, M. Kidd,<br />
G. Margolis, M. Roth, H. Sjogren, B. E. Tomlinson, H. M. Wisniewski)<br />
The Beginning:<br />
K. Ashe, USA Y. Ihara, Japan<br />
K. Beyreuther, Germany K. Iqbal, USA<br />
H. Braak, Germany C. Masters, Australia<br />
J.-P. Brion, Belgium<br />
A. Roses, USA<br />
M. Citron, USA G. Schellenberg, USA<br />
P. Davies, USA D. Schenk, USA<br />
M. De Leon, USA S. Sisodia, USA<br />
B. Frangione, USA P. St George-Hyslop, Canada<br />
A. Goate, USA R. Tanzi, USA<br />
M. Goedert, UK C. Wong, USA<br />
C. Haass, Germany B. Yankner, USA<br />
M. Hutton, USA S. Younkin, USA<br />
B. De Strooper, Belgium<br />
B. Hyman, USA<br />
W. Klunk, USA<br />
V. Lee, USA<br />
E. M<strong>and</strong>elkow, Germany<br />
J. Morris, USA<br />
R. Nitsch, Switzerl<strong>and</strong><br />
T. Saido, Japan<br />
C. Van Broeckhoven, Belgium<br />
M. Wolfe, USA<br />
Session 2<br />
Current Concepts<br />
ALZHEIMER: <strong>100</strong> YEARS AND BEYOND<br />
centenary meeting • november 2 – 5, 2006, tübingen, germany
Session 3<br />
Challenges for the Future<br />
M. Breteler, Netherl<strong>and</strong>s<br />
N. Fox, UK<br />
T. Golde, USA<br />
J. Hardy, USA<br />
T. Iwatsubo, Japan<br />
Z. Khachaturian, USA<br />
S. Paul, USA<br />
D. Price, USA<br />
D. Selkoe, USA<br />
L. Thal, USA<br />
J. Trojanowski, USA<br />
B. Winblad, Sweden<br />
For the Detailed Scientific Program please see www.alz<strong>100</strong>/scientific_meeting.html<br />
Neckar Tübingen<br />
ALZHEIMER: <strong>100</strong> YEARS AND BEYOND<br />
centenary meeting • november 2 – 5, 2006, tübingen, germany
Details & Additional Program<br />
CLINIC FOR PSYCHIATRY, UNIVERSITY OF TÜBINGEN<br />
The symposium will take place at this historic building, the Klinik für Gemüts- und<br />
Nervenheilkunde, where the “37. Versammmlung Südwestdeutscher Irrenärzte“<br />
gathered in 1906. At this meeting, on<br />
Nov 4, Alois Alzheimer presented his<br />
seminal Alzheimer case to his<br />
colleagues; among them were Franz<br />
Nissl, Robert Gaupp, Oswald Bumke,<br />
Hans Curschmann, Otto Binswanger<br />
<strong>and</strong> C.G. Jung, all of whom now have<br />
important places in the history of<br />
medicine. Prof. Gerhard Buchkremer<br />
has been the clinic’s director since<br />
1990.<br />
THEATER<br />
A new production of the theater play<br />
about the life <strong>and</strong> work of Alois Alzheimer<br />
written by Konrad <strong>and</strong> Ulrike Maurer, which<br />
has been sucessfully staged in Zürich <strong>and</strong><br />
Frankfurt, is being created by the new<br />
theater director of Tübingen (Simone Sterr).<br />
It will be put on stage in German but can<br />
equally be understood by English speakers<br />
as the translation will be provided via<br />
earphones. Attendees will be able to enjoy<br />
the play in a historic lecture hall at the<br />
<strong>Institut</strong>e of Anatomy.<br />
EXHIBITION<br />
In collaboration with Carl Zeiss Mikrosokopie we are planning to put up a small<br />
exhibition on the History of Microscopy in Alzheimer Research at the venue of the<br />
symposium. The exhibition will be open to the public on Thursday afternoon, to<br />
symposium attendees from Thursday afternoon until Saturday afternoon.<br />
ALZHEIMER: <strong>100</strong> YEARS AND BEYOND<br />
centenary meeting • november 2 – 5, 2006, tübingen, germany
CONFERENCE DINNER<br />
The conference dinner will be held at the<br />
Museum Restaurant, the same location<br />
where the participants of the gathering<br />
had dinner <strong>100</strong> <strong>years</strong> ago.<br />
ALZHEIMER’S BIRTHPLACE<br />
On Sunday, Nov 5, participants will have the opportunity to visit Alois Alzheimer’s<br />
birthplace. The 19th century house has been carefully restored <strong>and</strong> exhibits little<br />
treasures such as a microscope Alzheimer worked with <strong>and</strong> the original medical<br />
record <strong>and</strong> brain sections of Auguste D. This<br />
historical site gives you the rare opportunity to<br />
gain valuable insight into Alzheimer’s life <strong>and</strong><br />
research work. It is located in Marktbreit, a<br />
charming old town approx. 150 km southeast of<br />
Frankfurt <strong>and</strong> thus lies nearly en route to Frankfurt<br />
from Tübingen. On Sunday there will be a bus<br />
transfer (of 2 ½ hours) from Tübingen to Marktbreit<br />
leaving around 9 am. From there you can either<br />
take the bus back to Tübingen or take the train to<br />
Frankfurt airport (1 1 ½ - 2 hours).<br />
Alzheimer’s biographers, Konrad und Ulrike<br />
Maurer, will be your guides for the entire day, give<br />
you a tour through the town <strong>and</strong> birthplace, <strong>and</strong><br />
will do their best to answer all your questions<br />
regarding Alois Alzheimer’s life <strong>and</strong> work.<br />
CITY TOURS<br />
On Thursday afternoon city tours through the<br />
beautiful old city of Tübingen will be offered in both<br />
English <strong>and</strong> German. Emphasis will be on the history<br />
of science (e. g. on the work of Friedrich Miescher,<br />
who discovered the DNA in his laboratory at the<br />
local castle <strong>and</strong> following Alois Alzheimer’s tracks)<br />
<strong>and</strong> famous German poets <strong>and</strong> thinkers. For further<br />
information on the city of Tübingen please see also<br />
the city’s homepage: www.tuebingen.de/en<br />
ALZHEIMER: <strong>100</strong> YEARS AND BEYOND<br />
centenary meeting • november 2 – 5, 2006, tübingen, germany
General Information<br />
LOCATION<br />
Symposium:<br />
University Clinic for Psychiatry<br />
Osi<strong>and</strong>erstraße 25<br />
D - 72076 Tübingen<br />
Germany<br />
Public Session:<br />
Neue Aula, University of Tübingen<br />
Wilhelmstraße 7<br />
D - 72076 Tübingen<br />
Germany<br />
LANGUAGE<br />
English is the official language of the symposium. The public session <strong>and</strong> the theater<br />
performance on Thursday, Nov 2, will be held in German.<br />
CLIMATE<br />
The average November temperature in<br />
Tübingen is between 3 – 14 °C. We hope we will<br />
enjoy some beautiful fall days but advisably you<br />
should also be prepared for some rain.<br />
AIRPORT INFORMATION<br />
Most airplanes from overseas arrive in Frankfurt,<br />
which is located approximatly 250 km north of<br />
Tübingen. The trainride from Frankfurt to Tübingen<br />
via Stuttgart takes 2 – 3 hours, during the day<br />
trains run every 30-60 minutes.<br />
Stuttgart airport is located approx. 50 km north of<br />
Tübingen, which you can then reach by taxi, bus<br />
or train. Depending on means of transport the<br />
journey will take 30-80 minutes.<br />
ALZHEIMER: <strong>100</strong> YEARS AND BEYOND<br />
centenary meeting • november 2 – 5, 2006, tübingen, germany
REGISTRATION<br />
There will be no registration fee, but due to space limitations participation will<br />
unfortunately have to be limited to 181 people. For further information please see<br />
www.alz<strong>100</strong>.de/registration/html.<br />
Please note that we are planning to broadcast the entire conference as a live video<br />
stream via Internet <strong>and</strong> to produce a DVD which will be available after the meeting.<br />
For further information please see www.alz<strong>100</strong>.de/live_video.html<br />
HOTEL ACCOMMODATION<br />
The booking of hotel rooms for speakers will be organized by the administrative<br />
secretariat. Other participants should please make their bookings through our<br />
homepage www.alz<strong>100</strong>.de, where a Accommoation Form can be downloaded.<br />
LIST OF CURRENT SPONSORS<br />
Abbott GmbH<br />
Boehringer Ingelheim<br />
Eisai GmbH<br />
Elan Pharmaceuticals<br />
Hoffmann-La Roche<br />
Novartis GmbH<br />
LOCAL ORGANIZATION<br />
<strong>Hertie</strong> <strong>Institut</strong>e for Clinical Brain Research<br />
Department of Cellular Neurology<br />
Prof. Dr. Mathias Jucker<br />
Otfried-Müller-Str. 27<br />
D - 72076 Tübingen, Germany<br />
Administrative Secretariat<br />
Simone Eberle<br />
Phone: +49-7071-29 81947<br />
Fax: +49-7071-21 4521<br />
e-mail: info@alz<strong>100</strong>.de<br />
www.hih-tuebingen.de/en/<br />
www.alz<strong>100</strong>.de<br />
The latest version of the program can be downloaded here:<br />
http://www.hih-tuebingen.de/en/zellbiologie/congresses-organization/<br />
www.alz<strong>100</strong>.de<br />
Please address suggestions, comments, questions, <strong>and</strong> potential sponsoring to the organizers<br />
at info@alz<strong>100</strong>.de.<br />
ALZHEIMER: <strong>100</strong> YEARS AND BEYOND<br />
centenary meeting • november 2 – 5, 2006, tübingen, germany
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