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fall ’12 vol. 25 · no. o3<br />

12<br />

18<br />

Web-Only Content<br />

Meet some of the behind-the-scenes specialists<br />

who help modern science get done.<br />

Turtles and snakes and frogs, oh my! View the<br />

critters discovered during a herpetological<br />

survey at Janelia Farm.<br />

Read a Q&A with computer scientist<br />

Hanchuan Peng on developing sophisticated<br />

ways to make sense of biological images.<br />

Watch a fruit fly embryo develop and follow a<br />

dragonfly as it captures its prey, thanks to the<br />

latest developments in visualization techniques.<br />

Learn about the technology that lets<br />

researchers watch a heart grow, one vibrant<br />

cell at a time.<br />

24 30<br />

GO GREEN<br />

Prefer to receive your<br />

Bulletin digitally? Go to<br />

hhmi.org/bulletin/subscribe.<br />

Features<br />

cover story<br />

THE INDISPENSABLES<br />

12 The backbone of most labs, these quiet<br />

heroes do it all and then some.<br />

avant garde scientist<br />

18 With an outsider’s perspective,<br />

Leslie Vosshall has changed thinking<br />

about the meaning of olfaction—<br />

for humans and insects.<br />

THE FAT YOU CAN’T SEE<br />

24 In growing numbers of people, the liver<br />

holds a hidden, dangerous store of fat.<br />

Finding the triggers is step one.<br />

the view from here<br />

30 Unbounded creativity—and powerful<br />

computers—make possible the latest<br />

devices designed to peer into the<br />

deepest recesses of organs and cells.<br />

Departments<br />

PRESIDENT’S LETTER<br />

03 Stabilizing Forces<br />

CENTRIFUGE<br />

04 Good Stewards<br />

05 Undercover Triathlete<br />

06 Stepping into Sustainability<br />

UPFRONT<br />

08 Push and Pull<br />

10 Cancer’s Dead End<br />

PERSPECTIVES AND OPINIONS<br />

34 Connecting Cultures<br />

36 Q&A—What part of your job would<br />

people find the most surprising?<br />

CHRONICLE<br />

Science Education<br />

38 Teaching Genomics, Plainly<br />

<strong>Institute</strong> News<br />

40 HHMI Awards $50 Million to Colleges<br />

40 Fifty International Students Get<br />

Support from HHMI<br />

41 <strong>Medical</strong> Fellows Get a Chance to<br />

Try Research<br />

41 2012 Holiday Lectures on Science—<br />

Changing Planet: Past, Present, Future<br />

Lab Book<br />

42 The Yin and Yang of Plant Defense<br />

43 Like a Chinese Finger Trap<br />

44 Wiring the Brain<br />

Ask a Scientist<br />

45 Why do we develop distastes for<br />

certain foods?<br />

Nota Bene<br />

46 News of recent awards and other<br />

notable achievements<br />

OBSERVATIONS<br />

The Training Pipeline<br />

VISIT THE BULLETIN ONLINE FOR ADDITIONAL CONTENT AND ADDED FEATURES: www.hhmi.org/bulletin COVER IMAGE: CHRIS KING

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