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Astrup A et al. Am J Clin - American Heart Association

Astrup A et al. Am J Clin - American Heart Association

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RCTs with high PUFA and reduced SFA<br />

intake: benefici<strong>al</strong> effects on CVD<br />

V<strong>et</strong>eran Affairs; n=846; randomization to 40% fat di<strong>et</strong>, low<br />

SFA (9%) and cholesterol, high PUFA; reduction in tot<strong>al</strong><br />

CVD<br />

Dayton <strong>et</strong> <strong>al</strong>. Circulation 1969.<br />

Finnish Ment<strong>al</strong> Hospit<strong>al</strong> Study; n=676 men; 6 yr crossover<br />

study with low SFA (9.1%) and cholesterol, high PUFA;<br />

reduced cholesterol, CHD and coronary death<br />

Turpeinen <strong>et</strong> <strong>al</strong>. Int J Epidem 1979<br />

Oslo Di<strong>et</strong> <strong>Heart</strong>; n=412 men post-MI, rand to 40% fat<br />

(SFA=8.5%), high PUFA di<strong>et</strong>; reduced coronary death<br />

Leren P. Acta Med Scan 1966, Circ 1970

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