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Ischemic Stroke - Hennepin County Medical Center

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News Notes<br />

Team releases data on stroke<br />

treatment times at 2008 International<br />

<strong>Stroke</strong> Conference cont.<br />

<br />

<br />

<br />

<br />

A 24/7 dedicated stroke responder team,<br />

which included neurology residents, vascular<br />

neurology fellows, and neurology staff.<br />

A dedicated stroke pager for each team<br />

member and a system that allowed all<br />

pagers to be activated simultaneously when<br />

a potential stroke patient was en route.<br />

24/7 availability of neurology and<br />

radiology staff members to assist the<br />

emergency department.<br />

Protocols developed for evaluation<br />

and treatment of potential ischemic<br />

stroke patients.<br />

Before/after data show significant shifts that<br />

occurred after the stroke team was in place:<br />

<br />

<br />

In 2004, 9% of potential stroke patients<br />

received IV tPA. In 2006, that number rose<br />

to 17% of potential stroke patients, bringing<br />

the hospital in line with a handful of top<br />

national performers in tPA administration.<br />

In 2004, the mean door-to-needle time (e.g.<br />

the time from patient arrival to commencement<br />

of IV tPA) was 73 minutes. In 2006,<br />

that number dropped to 43 minutes.<br />

However, the number of patients receiving IV<br />

tPA decreased slightly and the mean door-toneedle<br />

time increased slightly in 2007, suggesting<br />

the importance of continued vigilance in<br />

speed of treatment for stroke patients.<br />

The presentation is available online for a<br />

fee. To purchase it and/or other educational<br />

presentations from the conference, visit<br />

www.scienceondemand.org and search under<br />

“2008 International <strong>Stroke</strong> Conference.”<br />

_____________________________________<br />

Clinical trials underway through the<br />

NETT Network<br />

Each year, more than one million Americans<br />

experience some type of acute devastating<br />

neurological illness or injury, ranging from<br />

ischemic stroke, to head and spinal cord<br />

injuries, to bacterial meningitis. <strong>Medical</strong> management<br />

of these problems often is hampered<br />

because treatments are understudied, based<br />

on limited evidence, or ineffective. A new network<br />

of hospitals is launching multi-centered<br />

clinical trials that will benefit patients with<br />

neurology illnesses and injuries.<br />

In 2003, a group of emergency room physicians<br />

and neurologists from across the U.S.<br />

met to discuss the problem and formed the<br />

Neurological Emergencies Treatment Trial<br />

(NETT) Network. The NETT Network, which<br />

recently has received funding from the National<br />

Institute of Neurological Disorders and <strong>Stroke</strong>,<br />

is a nationwide effort to improve the outcomes<br />

of these patients through interventional clinical<br />

research, focused on the emergent phase of<br />

patient care.<br />

The NETT Network aims to conduct simple<br />

multi-centered clinical trials of potential new<br />

therapies for a wide range of neurological problems.<br />

Each research study conducted by the<br />

NETT will be streamlined, with simple research<br />

questions that can be answered through the<br />

collection of a minimal amount of data at the<br />

patients’ bedside. The NETT Network includes<br />

academic centers as well as community and<br />

rural sites in order to enroll patients who are<br />

cared for in diverse settings. Several Minnesota<br />

hospitals will be participating and will assist in<br />

enrolling patients in future clinical research trials.<br />

For more information, visit nett.umich.edu/nett.<br />

20 | Approaches in Critical Care | December 2008

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