PD Dr. Oliver T. Fackler Department of Virology University ... - HBIGS
PD Dr. Oliver T. Fackler Department of Virology University ... - HBIGS
PD Dr. Oliver T. Fackler Department of Virology University ... - HBIGS
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
PUBLICATIONS (10 most important publications):<br />
Haller C, Rauch S, Michel N, Hannemann S, Keppler OT, <strong>Fackler</strong> OT (2006) The HIV-1<br />
pathogenicity factor Nef interferes with maturation <strong>of</strong> stimulatory T-lymphocyte contacts by<br />
modulation <strong>of</strong> N-Wasp activity. J Biol Chem 281: 19618-19630.<br />
Keppler OT, Tibroni N, Venzke S, Rauch S, <strong>Fackler</strong> OT (2006) Modulation <strong>of</strong> Specific<br />
Surface Receptors and Activation Sensitization in Resting Primary CD4+ T-Lymphocytes by<br />
the Nef Protein <strong>of</strong> HIV 1. J Leukoc Biol 79: 616-627.<br />
Michel N, Allespach I, Venzke S, <strong>Fackler</strong> OT*, Keppler OT* (2005) HIV Nef induces<br />
superinfection immunity by a dual strategy to downregulate cell surface CCR5 and CD4. (*<br />
corresponding authors). Curr Biol 15: 714-723.<br />
Krautkrämer E, Giese SI, Gasteier JE, Muranyi W, <strong>Fackler</strong> OT (2004) HIV-1 Nef activates<br />
Pak via recruitment into lipid rafts. J Virol 78: 4085-4097<br />
Gasteier JE, Madrid R, Krautkrämer E, Schröder S, Muranyi W, Benichou S, <strong>Fackler</strong> OT<br />
(2003) Activation <strong>of</strong> the Rac interaction partner formin homology 2 domain containing 1<br />
(FHOD1) induces actin stress fibers via a ROCK dependent mechanism. J Biol Chem 278:<br />
38902-38912.<br />
<strong>Fackler</strong> OT, Baur AS (2002) Live and let die: Functions <strong>of</strong> Nef beyond HIV replication.<br />
Immunity 16: 493-497.<br />
<strong>Fackler</strong> OT, Wolf D, Weber HO, Laffert B, D’Aloja P, Schuler-Thurner B, Geffin R, Saksela K,<br />
Geyer M, Peterlin BM, Schuler G, Baur AS (2001) A natural variability in the proline-rich motif<br />
<strong>of</strong> Nef modulates HIV-1 replication in primary T-cells. Curr Biol 11: 1294-1299.<br />
<strong>Fackler</strong> OT, Peterlin BM (2000) Endocytic entry <strong>of</strong> HIV-1. Curr Biol 10: 1005-1008.<br />
<strong>Fackler</strong> OT, Lu X, Frost JA, Geyer M, Jiang B, Luo W, Abo A, Alberts AS, Peterlin BM (2000)<br />
Pak1 plays a critical role in cellular activation by Nef. Mol Cell Biol 20: 2619-2627. [cover<br />
titel]<br />
<strong>Fackler</strong> OT, Luo W, Geyer M, Alberts AS, Peterlin BM (1999) Activation <strong>of</strong> Vav by Nef<br />
induces cytoskeletal rearrangements and downstream effector functions. Mol Cell 3: 729-<br />
739.