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Dichlorvos (DDVP) Risk Characterization Document - California ...

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USDA 1991 Total Diet Study (FDA, 1992). USEPA estimates of chronic exposure are also in Table 18<br />

and were 1/4 to 1/2 fold of those by DPR.<br />

Commodity contribution analysis was conducted to determine the critical commodities in the<br />

determination of total exposure (Table 19). Residues in cereal grains (28.2-30.9% of total exposure)<br />

and dairy products (25.4 to 51.25) were the major contributors toward the exposure levels of U.S.<br />

population, non-nursing, and children population subgroups.<br />

Lifetime Exposure<br />

The potential lifetime exposure to <strong>DDVP</strong> was evaluated based on the chronic dietary <strong>DDVP</strong> level of<br />

0.22 ug/kg-day (DPR) and 0.036 ug/kg-day (USEPA) for the US population (Table 18).<br />

Table 18. Potential acute and chronic dietary exposures to <strong>DDVP</strong> a .<br />

DPR DPR USEPA<br />

Acute exposure Chronic exposure Chronic exposure<br />

95th percentile of annual average annual average<br />

Population subgroups exposure (ug/kg-day) (ug/kg-day) (ug/kg-day)<br />

US Population, all seasons 0.91 0.22 0.036<br />

Western Region 0.88 0.22 0.038<br />

Hispanics 1.00 0.24 0.038<br />

Non-Hispanic Whites 0.87 0.22 0.036<br />

Non-Hispanic Blacks 1.04 0.26 0.031<br />

Non-Hispanic Other 1.13 0.28 0.035<br />

Infants (nursing, < 1 year) 0.62 0.06 0.019<br />

Infants (non-nursing, < 1 year) 1.44 0.24 0.063<br />

Children (1-6 years) 1.65 0.53 0.076<br />

Children (7-12 years) 1.15 0.35 0.053<br />

Females (13-19 years) 0.64 0.20 0.030<br />

(not pregnant, not nursing)<br />

Females (13+ years) 0.51 0.17 0.027<br />

(pregnant, not nursing)<br />

Females (13+ years) 0.52 0.18 0.034<br />

(nursing)<br />

Females (20+ years) 0.50 0.16 0.026<br />

(not pregnant, not nursing)<br />

Males (13-19 years) 0.69 0.24 0.036<br />

Males (20+ years) 0.57 0.18 0.029<br />

Seniors (55+ years) 0.49 NA b NA b<br />

a/<br />

b/<br />

c/<br />

Exposure levels have been rounded off to 3 significant figures.<br />

Chronic exposure data for this age group alone are not available.<br />

Data from Schaible, 1995.<br />

67

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