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PPT slides handout as PDF - the Department of Animal Sciences

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<strong>Animal</strong>/Dairy Science 434<br />

Lec 2:<br />

Female comparative anatomy;<br />

History <strong>of</strong> Reproductive Physiology<br />

Ovarian Differences<br />

Cow<br />

Mare<br />

Kangaroo Rat Human<br />

Sow<br />

Cow, Sow, Ewe, Human<br />

• Cortex on outside<br />

• Ovulation can occur on<br />

any point <strong>of</strong> <strong>the</strong> ovary<br />

Mare<br />

• Inversion <strong>of</strong> <strong>the</strong> cortex and<br />

medulla.<br />

• Ovulation occurs at <strong>the</strong><br />

Ovulation Fossa<br />

Cow<br />

Preovulatory<br />

Tertiary<br />

Follicle<br />

Sow<br />

Blood vessels<br />

and connective<br />

tissue in medulla<br />

Uterine and Cervical<br />

Differences<br />

Sow<br />

Internal<br />

CL<br />

Cow<br />

Mare<br />

Mare<br />

Oposum<br />

Duplex<br />

Rabbit, Mouse<br />

Ewe<br />

Bicornuate<br />

Cow<br />

Sow<br />

2 Uterine Horns<br />

2 Cervixes<br />

2 Vagin<strong>as</strong> 1 Vagina<br />

Smaller<br />

uterine<br />

horns<br />

1 Vagina<br />

1 Cervix<br />

1 Uterine Body<br />

2 Uterine Horns<br />

Large<br />

uterine<br />

horns


Bicornuate<br />

Bicornuate<br />

Mare<br />

Dog<br />

Large uterine body<br />

Smaller uterine horns<br />

1 Vagina<br />

1 Cervix<br />

1 Uterine Body<br />

2 Uterine Horns<br />

1 Vagina<br />

1 Cervix<br />

1 Uterine Body<br />

2 Uterine Horns<br />

Cat<br />

Small uterine body<br />

Long uterine horns<br />

Simplex<br />

Human Tract<br />

Woman<br />

Large uterine body<br />

No uterine horns<br />

1 Vagina<br />

1 Cervix<br />

1 Uterine Body<br />

Human Tract<br />

A 47-year old woman underwent a hysterectomy for<br />

excessively heavy menses. She had previously had four<br />

normal deliveries. This structure w<strong>as</strong> removed, what is<br />

wrong?


• Cervix is composed<br />

<strong>of</strong> thick connective<br />

tissue<br />

Cervix<br />

Cow h<strong>as</strong> 4-5<br />

annular rings<br />

Uterine Body<br />

Internal Cervical Os<br />

COW<br />

• Mucus is secreted<br />

near <strong>the</strong> time <strong>of</strong><br />

breeding and<br />

ovulation.<br />

No<br />

obstacles<br />

Mare<br />

Uterine Body<br />

Longitudinal<br />

Folds<br />

Interdigitating<br />

pads<br />

Sow<br />

Uterine Body<br />

External Cervical Os<br />

Fornix Vagina<br />

No<br />

fornix<br />

vagina<br />

Vagina<br />

Vagina<br />

Vagina<br />

Cervix<br />

Cervix<br />

COW<br />

Internal Os<br />

Cervical<br />

Ring<br />

Cervical<br />

Ring<br />

Cervical<br />

Folds<br />

Fornix<br />

Fornix<br />

FV<br />

IP<br />

External Os<br />

EWE<br />

Fornix<br />

Anterior Vagina<br />

Anterior Vagina<br />

Sow<br />

Mare<br />

External Genitalia<br />

Mare Cow Sow<br />

What is this?<br />

Ewe


Human Tract<br />

External Genitalia<br />

Vagina Anterior Vagina Posterior Vagina (Vestibule)<br />

Cervix<br />

Columnar<br />

Epi<strong>the</strong>lium<br />

Fornix<br />

Urethra<br />

Stratified<br />

Squamous<br />

Epi<strong>the</strong>lium<br />

Vulva-<br />

Vaginal<br />

Sphincter<br />

(Hymen)<br />

Avian<br />

Female<br />

Anatomy<br />

Magnum<br />

Isthmus<br />

Uterus<br />

Infundibulum<br />

Ovary<br />

Oviduct<br />

Shell Gland<br />

Intestine<br />

perivitelline<br />

membrane<br />

chalazae<br />

albumen<br />

shell membrane<br />

cleaving bl<strong>as</strong>todisc<br />

Submucosa<br />

Mucosa<br />

Submucosa<br />

vagina<br />

cloaca<br />

Right<br />

Oviduct<br />

Left side <strong>of</strong> Reproductive Tract Develops!!<br />

24 hrs<br />

50K cells<br />

shell<br />

Chicken Tract<br />

Ovary<br />

Chicken Ovary<br />

Hierarchal<br />

Follicles<br />

Magnum<br />

Intestine<br />

Shell Gland


Ovary with<br />

large follicles<br />

removed<br />

Chicken Reproductive Tract<br />

Isthmus<br />

Infundibulum<br />

Magnum<br />

Shell Gland<br />

Ruptured follicle<br />

Cloaca<br />

Follicles<br />

Infundibulum<br />

Cloaca<br />

Vagina<br />

Vaginal<br />

opening<br />

Intestine<br />

opening<br />

Cloaca <strong>of</strong> Chicken<br />

Historical Development <strong>of</strong><br />

Reproductive Physiology<br />

Intestine<br />

opening<br />

Aristotle 384-322 BC<br />

Generation<br />

<strong>of</strong> <strong>Animal</strong>s<br />

• Fetus arises from<br />

menstrual blood<br />

• Seminal pl<strong>as</strong>ma initiates<br />

<strong>the</strong> conversion <strong>of</strong><br />

menstrual blood<br />

Vagina opening<br />

• Semen from all parts <strong>of</strong><br />

body


The Age <strong>of</strong> Gross Anatomy<br />

• Fallopius (1562)<br />

– Describes <strong>the</strong> oviduct<br />

• Coiter (1573)<br />

– Describes <strong>the</strong> corpus luteum<br />

• Regnier de Graff (1672)<br />

– Describes <strong>the</strong> antral follicle (Graafian Follicle)<br />

Development <strong>of</strong> <strong>the</strong> Microscope<br />

• van Leewenhoek (1677)<br />

– Describes spermatozoa<br />

in semen<br />

What is <strong>the</strong> role <strong>of</strong> spermatozoa?<br />

• Spallanzani (1780)<br />

– Sperm were <strong>the</strong> fertilizing agent in semen<br />

– Successful artificial insemination <strong>of</strong> a dog<br />

• Dum<strong>as</strong> (1825)<br />

– Proves sperm <strong>the</strong> fertilizing agent<br />

Modern Reprod. Physiology<br />

• Gonads produce steroid hormones<br />

• Regulation <strong>of</strong> estrous cycles in females<br />

• Radioimmuno<strong>as</strong>say (RIA)<br />

• Artificial Insemination<br />

• Cryopreservation<br />

• Prostaglandin used to control estrous<br />

cycles<br />

• Biotechnology<br />

Approach to Applications<br />

• Develop b<strong>as</strong>ic knowledge <strong>of</strong> how<br />

system works<br />

• Investigate methods that can perturb<br />

<strong>the</strong> system<br />

• Manipulate <strong>the</strong> system to improve<br />

reproduction<br />

– Estrus Synchronization<br />

Enhancing Reproduction<br />

• Small improvements have pr<strong>of</strong>ound<br />

effects on production<br />

– 3% improvement in birth rate results in an<br />

additional:<br />

• 1 million beef calves/year<br />

• 3.2 million pigs/year<br />

• 3.7 million gallons <strong>of</strong> milk/year


Current Trends<br />

Limiting Reproduction<br />

Insects<br />

Pets<br />

Production<br />

Metabolic<br />

and<br />

Physiologic<br />

Changes<br />

Reproduction<br />

Humans<br />

• Continuing need to:<br />

– improve reproductive performance<br />

– understand how to apply new technology<br />

• Ovsynch<br />

• Clonning<br />

Wildlife

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