Rheumatoid Arthritis

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<strong>Rheumatoid</strong> factor • Antibodies against human IgG Fc • 1-5% of normal people • Also in chronic infections and inflammation eg TB, endocarditis and liver cirrhosis
Radiological diagnosis • Periarticular soft tissue swelling • Periarticular osteopaenia • Joint space narrowing • Marginal joint erosions leading eventually to complete joint destruction • Subchondral cysts • Compressive changes due to collapse of osteoporotic subchondral bone eg protrusio acetabuli at hip
Page 1 and 2:
Rheumatoid Arthritis Dr. C. C. Viss
Page 3 and 4:
Rheumatoid arthritis • Most commo
Page 5 and 6: Effects of RA • Systemic disease
Page 9 and 10: Mechanisms of joint damage • Syno
Page 12 and 13: ACR Classification Criteria (4/7)
Page 14 and 15: Articular involvement Any synovial
Page 16: Hand • MCP joints - Synovitis - U
Page 21: Elbow • Synovitis • Flexion con
Page 24: Foot •MTP - Synovitis - Subluxati
Page 27: Knee • Synovitis • Effusions
Page 31: Cervical spine • Involved in 70%
Page 34 and 35: Other joints • TMJ: reduced mouth
Page 36 and 37: Non-articular manifestations • Ge
Page 40 and 41: Non-articular manifestations • He
Page 42: Non-articular manifestations • Sk
Page 49 and 50: Complications
Page 51: Complications • Felty syndrome -
Page 54 and 55: Special investigations
Page 60 and 61: Serial X-rays of a knee in RA
Page 62 and 63: Multidisciplinary Care • Rheumato
Page 64 and 65: Medical Treatment Symptomatic: NSAI
Page 66: Treatment • Rest vs exercise •
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Rheumatoid Arthritis

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